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Cellular Origins appoints Geoffrey Hodge as Non-Executive Director

Appointment brings additional significant strategic, technical and commercial experience to the Board.

From Cellular Origins 16 Jul 2024

Chronic Urticaria: Addressing unmet needs, emerging therapies, and advances in personalized treatment approaches

Emerging personalized treatment approaches for chronic urticari.

16 Jul 2024

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children's Hospital has revealed that an immune protein impacts neuronal protein synthesis in the aging brain.

15 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Allen Institute launches neuroscience initiatives on perception, recognition, and psychedelics

How do neurons react to magic mushrooms? What happens in the brain when we see motion, or when we recognize grain patterns in a piece of wood? How do our brains track the subtle changes in our friends' appearances over time?

15 Jul 2024

Triad of immune cells key to successful cancer immunotherapy, study finds

There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully - completely eliminating or greatly reducing cancer in particular patients - other times they don't work at all. It's a mystery.

15 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors.

15 Jul 2024

Genetic marker predicts gabapentin response in chronic pelvic pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

15 Jul 2024

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Drastic caloric restriction by athletes diminishes performance and compromises the immune system

Drastically cutting back on caloric intake to lose weight ahead of competition is commonplace among athletes.

15 Jul 2024

Unraveling the role of liquid-liquid phase separation in neurodegenerative diseases

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study.

15 Jul 2024

Mogrify appoints Dr. Jonathan Appleby as Chief Scientific Officer

Strategic hire bolsters executive leadership team as Company progresses multiple therapeutic programs toward and into clinical development.

From Mogrify 15 Jul 2024

COVID-19 leads to long-term changes in the immune system, study shows

In a study recently published in the renowned journal "Allergy", a MedUni Vienna research team shows that COVID-19 leads to considerable long-term changes in the immune system, even in mild cases.

15 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

15 Jul 2024

Hidden threats in plant-based diets: Rising allergies to lesser-known legumes

Researchers have identified emerging legume allergens like peas, lentils, and lupines, calling for more extensive studies and better diagnostics to manage increasing allergic reactions. The popularity of plant-based diets has brought new allergenic challenges to light.

15 Jul 2024

Review highlights unique characteristics and mechanisms of ferroptosis

Junxia Min, Fudi Wang, et al., at Zhejiang University School of Medicine, China, provided an in-depth review on the programmed cell death known as ferroptosis, which is driven by iron-dependent lipid peroxidation.

14 Jul 2024

TurCaMPb: A novel tool for monitoring mitochondrial calcium dynamics

Mitochondria are crucial for maintaining calcium balance in cells, but their calcium dynamics are challenging to study due to pH changes in the mitochondrial matrix, and the lack of cyan-colored GECIs hinders the monitoring of calcium signals across different organelles and cell types.

14 Jul 2024

Cell News and Research

Cellular Origins appoints Geoffrey Hodge as Non-Executive Director

Chronic Urticaria: Addressing unmet needs, emerging therapies, and advances in personalized treatment approaches

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Researchers discover key functions of IRF1 in cancer progression and treatment response

Allen Institute launches neuroscience initiatives on perception, recognition, and psychedelics

Triad of immune cells key to successful cancer immunotherapy, study finds

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Genetic marker predicts gabapentin response in chronic pelvic pain

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Drastic caloric restriction by athletes diminishes performance and compromises the immune system

Unraveling the role of liquid-liquid phase separation in neurodegenerative diseases

Mogrify appoints Dr. Jonathan Appleby as Chief Scientific Officer

COVID-19 leads to long-term changes in the immune system, study shows

One-time prime editing targets common genetic cause of cystic fibrosis

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Hidden threats in plant-based diets: Rising allergies to lesser-known legumes

Review highlights unique characteristics and mechanisms of ferroptosis

TurCaMPb: A novel tool for monitoring mitochondrial calcium dynamics

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