Clinical Trial News and Research

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Cardiovascular disease patients with internal bleeding more likely to be diagnosed with cancer

Patients with cardiovascular disease who develop major internal bleeding are much more likely to be diagnosed with cancer, a large international clinical trial has found.

27 Aug 2018

Use of medication reminder apps increases people's adherence to cardiovascular medication

We use them for everything from banking to workouts, and now research from the University of Sydney shows mobile apps could potentially save lives by helping people with coronary heart disease keep on top of their medication.

27 Aug 2018

$Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction$

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Data from the TRANSITION study presented today at the European Society of Cardiology Congress in Munich, Germany has shown that Entresto® can be initiated early and safely in a wide range of heart failure patients with reduced ejection fraction who have been stabilized after hospitalization due to an acute heart failure episode.

25 Aug 2018

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

Forbius announced today that it has been awarded a Product Development grant totaling $18.75 million from the Cancer Prevention and Research Institute of Texas.

25 Aug 2018

Surgeons test new device that keeps the liver warm and circulates blood during transport

Since the first liver transplant in 1963, donated livers have been immersed in an icy cold fluid in a cold storage system for transport, similar in principle to ice chests used for picnics and trips to the beach.

25 Aug 2018

Hand-held ophthalmology probe can image photoreceptors in the eyes of infants

Duke University researchers have developed a handheld probe that can image individual photoreceptors in the eyes of infants.

24 Aug 2018

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

The Muscular Dystrophy Association today announced the award of 34 new grants totaling more than $9.9 million for its summer round of funding. These new grants represent a continued commitment by MDA to fund groundbreaking research that will accelerate treatments and cures for the more than 40 diseases in its program.

24 Aug 2018

UAB receives NIH grant to continue evaluation of new medication for IPF

The University of Alabama at Birmingham has received a grant from the National Institutes of Health totaling $8.9 million to fund a multiyear program evaluating the role of a new medication in a clinical trial for patients suffering from idiopathic pulmonary fibrosis

24 Aug 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

AVITA Medical: Clinical trial results demonstrate safety, efficacy of RECELL Device in treating burn patients

AVITA Medical today announced that results from two U.S. pivotal clinical trials demonstrating the effectiveness and clinical benefits of the RECELL Autologous Cell Harvesting Device were presented in the plenary session at the U.S. Defense Department Military Health System Research Symposium (MHSRS) in Kissimmee, Florida.

23 Aug 2018

Pediatric antibiotic prescriptions lead to nearly 70,000 ER visits in the U.S. each year

The use of antibiotics drives the development of antibiotic resistance, a major threat to public health worldwide. But these drugs also carry the risk of harm to individual patients, including children.

23 Aug 2018

Immunotherapy combination shrinks melanoma that has spread to the brain

Combination immunotherapy shrank melanoma that has spread to the brain in more than half of the patients in a clinical trial reported in the New England Journal of Medicine led by an investigator at The University of Texas MD Anderson Cancer Center.

23 Aug 2018

Scientists publish study results of AAV therapy product for treatment of RHO-adRP

Ophthotech Corporation announced today that scientists at the University of Pennsylvania and University of Florida published proof-of-concept study results on an adeno-associated virus gene therapy product candidate for the treatment of rhodopsin-mediated autosomal dominant retinitis pigmentosa licensed by Ophthotech.

22 Aug 2018

FDA grants 510(k) clearance to market Gynesonics' Sonata System

Gynesonics, a women's healthcare company focused on the development of minimally invasive solutions for symptomatic uterine fibroids, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration to market its Sonata Sonography-Guided Transcervical Fibroid Ablation (Sonata) System.

22 Aug 2018

Federal grant extends and expands research into acute kidney failure

The National Institute of Diabetes and Digestive and Kidney Diseases has renewed a grant shared by the University of Alabama at Birmingham School of Medicine and the University of California at San Diego School of Medicine that will extend and expand research into acute kidney failure, or acute kidney injury, which affects about 1.2 million hospitalized patients per year and kills 70 to 80 percent of patients in intensive care units who develop the disease.

22 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Temple University Hospital becomes the first in U.S. to perform BLVR using Zephyr valve

Temple University Hospital has become the first U.S. center to perform bronchoscopic lung volume reduction using implantation of the Zephyr Endobronchial Valve to treat severe emphysema following U.S. FDA approval.

21 Aug 2018

A form of vitamin B3 shows potential to prevent acute kidney injury

Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries.

21 Aug 2018

Blood management program associated with fewer transfusions in orthopedic patients

A patient blood management program designed to limit the amount of transfused blood orthopedic patients undergoing common surgeries such as hip and knee replacement receive was associated with fewer transfusions, reduced blood use and improved outcomes, reports a study published in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists.

20 Aug 2018

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Aravive Biologics, Inc. announced today that the U.S. Food and Drug Administration has granted Fast Track Designation to AVB-S6-500 as a potential treatment for platinum-resistant recurrent ovarian cancer.

20 Aug 2018

Clinical Trial News and Research

Cardiovascular disease patients with internal bleeding more likely to be diagnosed with cancer

Use of medication reminder apps increases people's adherence to cardiovascular medication

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

Surgeons test new device that keeps the liver warm and circulates blood during transport

Hand-held ophthalmology probe can image photoreceptors in the eyes of infants

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

UAB receives NIH grant to continue evaluation of new medication for IPF

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

AVITA Medical: Clinical trial results demonstrate safety, efficacy of RECELL Device in treating burn patients

Pediatric antibiotic prescriptions lead to nearly 70,000 ER visits in the U.S. each year

Immunotherapy combination shrinks melanoma that has spread to the brain

Scientists publish study results of AAV therapy product for treatment of RHO-adRP

FDA grants 510(k) clearance to market Gynesonics' Sonata System

Federal grant extends and expands research into acute kidney failure

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Temple University Hospital becomes the first in U.S. to perform BLVR using Zephyr valve

A form of vitamin B3 shows potential to prevent acute kidney injury

Blood management program associated with fewer transfusions in orthopedic patients

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

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