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UK’s health performance declining compared with 14 EU countries over past 20 years

Six decades of universal free health care, the introduction of widespread public health initiatives (eg, tobacco control, cancer screening, and immunisation), and substantial increases in health expenditure have failed to improve the UK’s health outcomes or longevity ranking against the average of 14 other original members of the European Union, Australia, Canada, Norway, and the USA (EU15+) over the past 20 years.

6 Mar 2013

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed without chemotherapy.

6 Mar 2013

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer.

6 Mar 2013

Endocrine Society issues position statement on estradiol measurement

In a Position Statement unveiled today, The Endocrine Society advocates that all methods for measuring estrogens, which play a crucial role in human biology, be made traceable to a common standard.

6 Mar 2013

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Nikolai Begg grew up in a box of LEGO- bricks and hasn't stopped tinkering since. Today he is an accomplished inventor with a portfolio of novel medical devices. Begg is the recipient of the prestigious $30,000 Lemelson-MIT Student Prize for his inventions that are making surgical procedures less invasive.

6 Mar 2013

Deleting Plin2 gene prevents obesity in mice

Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.

6 Mar 2013

Microcystins in drinking water

An interview with Rohan Thakur, discussing the prevalence of microcystins in drinking water, and the use of LC-MS to identify cyanotoxins within water samples.

From Bruker Life Sciences Mass Spectrometry 5 Mar 2013

HIV might promote aging and disease progression in people with HCV, study results suggest

Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus, co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.

5 Mar 2013

Oxidative stress turns protein that protects healthy cells into executioner: Study

Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released today in the Proceedings of the National Academy of Sciences journal.

5 Mar 2013

New tool can accurately forecast malaria epidemics in northwestern India

Sea surface temperatures in the tropical South Atlantic Ocean can be used to accurately forecast, by up to four months, malaria epidemics thousands of miles away in northwestern India, a University of Michigan theoretical ecologist and her colleagues have found.

5 Mar 2013

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Interim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).

5 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.

28 Feb 2013

EpiCept fourth quarter revenue decreases to $0.1 million

EpiCept Corporation today announced operating and financial results for the fourth quarter and full year ended December 31, 2012, and provided an update on the Company's merger with Immune Pharmaceuticals, Ltd. (Immune).

28 Feb 2013

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

While history shows that a divided government can enact significant spending cuts as an alternative to sequesters, that doesn't appear to be the path Mr. Obama intends to follow. Instead of protecting civilian defense workers, the president will continue to force the Pentagon to buy biofuels at $27 per gallon to promote his green agenda.

27 Feb 2013

New findings could help develop treatments for inherited disorders

Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.

27 Feb 2013

Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

N-acetylcysteine improves graft survival following liver transplantation

Researchers from Italy have found that the antioxidant, N-acetylcysteine (NAC), when injected prior to harvesting of the liver, significantly improves graft survival following transplantation.

26 Feb 2013

Liver News and Research

UK’s health performance declining compared with 14 EU countries over past 20 years

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Endocrine Society issues position statement on estradiol measurement

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Deleting Plin2 gene prevents obesity in mice

Microcystins in drinking water

HIV might promote aging and disease progression in people with HCV, study results suggest

Oxidative stress turns protein that protects healthy cells into executioner: Study

New tool can accurately forecast malaria epidemics in northwestern India

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Stem cell line could also advance research into liver cancers, cystic fibrosis

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

EpiCept fourth quarter revenue decreases to $0.1 million

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

New findings could help develop treatments for inherited disorders

Wnt-induced Lgr5 expression marks stem cell production in the liver

N-acetylcysteine improves graft survival following liver transplantation

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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