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10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

Novel anti-rejection protocol should allow major improvement efficacy and quality of life after intestinal and multivisceral transplants

Transplant researchers at the University of Pittsburgh's Thomas E. Starzl Transplantation Institute have dramatically improved intestinal transplant graft survival, and reduced rejection and infection rates by successfully using a novel immunosuppression minimization protocol, thus improving patients' overall quality of life and avoiding the use of several anti-rejection drugs, which can cause serious infections and major complications.

13 Dec 2004

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

In laboratory tests on multiple myeloma cells, University of Rochester researchers found that this type of cancer expresses a protein that makes it an easy target for an existing class of diabetes drugs. After more investigation, they hope the discovery will lead to a new, targeted therapy for myeloma patients.

8 Dec 2004

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Results from a clinical trial presented at the American Society of Hematology 46th Annual Meeting and Exposition (ASH) demonstrated that Zevalin (ibritumomab tiuxetan), administered as a first-line therapy, induced a 100 percent response rate in a small population of patients with low-grate follicular lymphoma (FL).

6 Dec 2004

Single dose phase I data on CG53135 for the prevention of oral mucositis

CuraGen Corporation has announced results presented from a Phase I clinical trial with CG53135 for the prevention of oral mucositis (OM) in patients receiving high dose chemotherapy (HDCT) followed by autologous hematopoietic stem cell transplantation (AHSCT) at the ASH 46th Annual Meeting in San Diego, CA.

5 Dec 2004

3D MDCT accurate for imaging liver arteries

3D MDCT angiography is a more efficient way to classify liver arterial anatomy before liver surgery, according to researchers from Duke University in Durham, NC.

2 Dec 2004

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Higher incidence of rejection following early steroid withdrawal

A new study on early steroid withdrawal following liver transplantation found that there was a higher incidence of rejection and a lower incidence of glucose intolerance necessitating treatment for diabetes.

1 Dec 2004

Peripheral neuropathy in a patient with alcoholic cirrhosis is reversible

Organ damage that goes beyond the liver due to alcoholism is often seen as a barrier to liver transplantation, despite a lack of data on how a transplant affects these complications.

1 Dec 2004

Simple and inexpensive interventions can cut the number of catheter-related bloodstream infections

As many as 28,000 patients die each year in the U.S. because of catheter-related bloodstream infections, but doctors and nurses who implement simple and inexpensive interventions can cut the number of deaths to nearly zero, according to a study by Johns Hopkins researchers.

30 Nov 2004

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) have induced human insulin-producing cells of the pancreas to revert to islet precursor cells.

29 Nov 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Cells linked to asthma and eczema also help cure deadly illness in mice

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

20 Nov 2004

Stem cells can preserve and improve vision in eyes damaged by retinal disease

"These findings hold great promise for potential treatments for people suffering from macular degeneration, diabetic retinopathy and other retinal diseases," says Michael Young, PhD, an assistant scientist at Schepens Eye Research Institute and the lead author of the study.

18 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Virginia Commonwealth University engineers and scientists have developed and patented a unique technique to grow three-dimensional tissues and organs in a mold made from material the human body naturally uses to repair wounds, potentially eliminating the chance for rejection.

17 Nov 2004

Transplant News and Research

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

Novel anti-rejection protocol should allow major improvement efficacy and quality of life after intestinal and multivisceral transplants

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Single dose phase I data on CG53135 for the prevention of oral mucositis

3D MDCT accurate for imaging liver arteries

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Higher incidence of rejection following early steroid withdrawal

Peripheral neuropathy in a patient with alcoholic cirrhosis is reversible

Simple and inexpensive interventions can cut the number of catheter-related bloodstream infections

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

Cells linked to asthma and eczema also help cure deadly illness in mice

Stem cells can preserve and improve vision in eyes damaged by retinal disease

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Mast cells can provide protection from a potentially deadly condition known as sepsis

Sex genes of infectious fungus closely resemble human Y chromosome

Heart jacket effective treatment for heart failure

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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