Genetic News and Research

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Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

If your alertness and reaction time is see-sawing more than usual, you may be more at risk of a viral illness.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality.

3 Jan 2023

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic baz1b clues to the evolution of social behaviors in humans and domesticated species.

3 Jan 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023

What is the impact of COVID-19 on the human genetic architecture?

Researchers recently described the second update on the study of human genetic architecture with respect to the effect of coronavirus disease 2019 (COVID-19).

3 Jan 2023

Deep learning tool identifies mosaic mutations that cause disease

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because they exist in a tiny percentage of the cells.

2 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy.

2 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli.

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

Genetic News and Research

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

Researchers identify novel gene mechanism in most aggressive kidney cancers

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

What is the impact of COVID-19 on the human genetic architecture?

Deep learning tool identifies mosaic mutations that cause disease

Underlying genetic cause for MIS-C complications after COVID-19 identified

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Novel experimental approach slows physical decline and extends the lives of roundworms

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

AI can improve the effectiveness of colonoscopy in the presence of Lynch syndrome

Scientists gain new insights into the opposing actions of serotonin-producing nerve fibers in mice

Model provides new insights into how autism arises

A genome-based comparison of SARS-CoV-2 XBB recombinant and its parental lineage

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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