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TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T cells (Treg) to treat severe chronic inflammatory and autoimmune diseases, today announces the signature of a strategic R&D collaboration agreement with the University of British Columbia (UBC) in Vancouver, Canada, a leading global center for multidisciplinary research and teaching.

24 Oct 2016

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Researchers at the Medical University of South Carolina Hollings Cancer Center have discovered a mechanism that confers resistance to drugs used to treat certain types of acute myeloid leukemia (AML).

24 Oct 2016

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer.

21 Oct 2016

Targeting TASINs can be viable approach for preventing colon cancer, research reveals

A small molecule called TASIN-1 can selectively kill cells with a mutation that is considered to be a precursor to colon cancer, while sparing related normal cells, UT Southwestern Medical Center cancer biologists have demonstrated.

20 Oct 2016

Two leading non-profit organizations sign strategic affiliation to hasten drug development

The Scripps Research Institute and the California Institute for Biomedical Research - two leading non-profit research organizations - today announced the signing of a strategic affiliation that combines the two organizations into a new biomedical research entity with the tools and know-how to rapidly translate its scientific discoveries into life-saving medicines for the public benefit.

20 Oct 2016

Yale researchers identify chemical inhibitor that limits growth of lung tumor cells

A recently published Yale study may offer a new solution to fighting lung cancer.

20 Oct 2016

TUM scientists uncover novel mechanisms of action for skin disease medication

Imiquimod is a medication successfully used in the treatment of skin diseases. In addition to its known mechanism of action, it also triggers other processes in the body.

20 Oct 2016

Compound bearing hidden chirality can trigger autocatalytic preparation of chiral organic intermediates

The preparation of chiral compounds as intermediates in drug synthesis is one of the most important targets in synthetic organic chemistry.

20 Oct 2016

Einstein researchers awarded $2.6 million NIH grant to develop effective cancer immunotherapies

The National Institutes of Health has awarded two co-investigators at Albert Einstein College of Medicine a five-year, $2.6 million grant to make immunotherapy agents that more precisely and effectively treat a variety of cancers while causing far fewer side effects than current immunotherapies.

20 Oct 2016

Neu5Gc common in red meat increases risk of tumor formation

Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found.

19 Oct 2016

Study unravels how caloric restriction provides beneficial effects to the brain

Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood.

19 Oct 2016

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

A molecular signaling pathway identified by an international research team could be the basis of improved treatment for osteoporosis.

19 Oct 2016

Scientists discover new receptors for stomach bacterium Helicobacter pylori

A research group led by Prof. Markus Gerhard of the Technical University of Munich and Assistant Professor Dr. Bernhard B. Singer of the Institute for Anatomy at the Faculty of Medicine of the University of Duisburg-Essen at Essen University Medical Centre has discovered a completely new approach to preventing or treating infections with this bacterium as well as secondary complications.

19 Oct 2016

Modulating immune response may help the brain to better cope with neurodegeneration

Study suggests zebrafish might teach us how to tackle Alzheimer's disease: Patients with Alzheimer's or other neurodegenerative diseases progressively loose neurons yet cannot build new ones.

19 Oct 2016

Domain Therapeutics and Medicxi partner to launch Mavalon Therapeutics

Domain Therapeutics, a biopharmaceutical company that specializes in the discovery and development of G protein-coupled receptor (GPCR) drugs, today announces the creation of Mavalon Therapeutics, a company focused on stopping the progression of Parkinson’s disease.

19 Oct 2016

UCLA scientists take promising step towards killing mosquitoes that carry Zika virus and dengue fever

Five UCLA researchers were part of an international team that has used X-rays to reveal the structure of a molecule that is toxic to disease-carrying mosquitoes.

18 Oct 2016

Researchers discover new approach to preventing H. pylori linked to stomach infections

Researchers have discovered a new approach to preventing or treating a stomach bacterium associated with an increased risk of stomach cancer as well as gastritis and duodenal ulcers.

18 Oct 2016

Chemotherapy leads to drug-resistance in bladder cancer patients

Chemotherapy is indicated as the first line of treatment for advanced bladder cancer. New research by Weill Cornell Medicine and University of Trento scientists shows that while chemotherapy kills the most common type of bladder cancer, urothelial cancer, chemotherapy also shapes the genetic evolution of remaining urothelial cancer cell clones to become drug-resistant.

18 Oct 2016

IED detection technique could be potential diagnostic tool for dementia

Researchers from the University of Adelaide in South Australia developed the Improvised Explosive Device (IED) detection method in 2014, which used light intensity to determine the presence of explosive residue.

17 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Molecule News and Research

TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

Targeting TASINs can be viable approach for preventing colon cancer, research reveals

Two leading non-profit organizations sign strategic affiliation to hasten drug development

Yale researchers identify chemical inhibitor that limits growth of lung tumor cells

TUM scientists uncover novel mechanisms of action for skin disease medication

Compound bearing hidden chirality can trigger autocatalytic preparation of chiral organic intermediates

Einstein researchers awarded $2.6 million NIH grant to develop effective cancer immunotherapies

Neu5Gc common in red meat increases risk of tumor formation

Study unravels how caloric restriction provides beneficial effects to the brain

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

Scientists discover new receptors for stomach bacterium Helicobacter pylori

Modulating immune response may help the brain to better cope with neurodegeneration

Domain Therapeutics and Medicxi partner to launch Mavalon Therapeutics

UCLA scientists take promising step towards killing mosquitoes that carry Zika virus and dengue fever

Researchers discover new approach to preventing H. pylori linked to stomach infections

Chemotherapy leads to drug-resistance in bladder cancer patients

IED detection technique could be potential diagnostic tool for dementia

Penn researchers identify new immune system mechanism to fight against infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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