Clinical Trial News and Research

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University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

University Hospitals Seidman Cancer Center launched a new clinical trial for CAR-T, joining a select group of hospitals offering the therapy and a smaller group of hospitals manufacturing the CAR-T cells.

14 Aug 2018

New intervention to reduce risk of HIV in young transgender women

Young transgender women who took part in an intervention to reduce HIV transmission and acquisition had a greater reduction in condomless sex acts than young transgender women who received standard preventive care with testing for HIV/sexually transmitted infections and counseling in a randomized clinical trial.

13 Aug 2018

Researchers discover secret communication hotline between breast cancers and normal cells

Australian researchers have uncovered a secret communication hotline between breast cancers and the normal cells surrounding them. Importantly, the messages sent back and forth between the normal and tumour cells encourage the cancer to survive and to become more aggressive.

13 Aug 2018

Experts highlight key knowledge gaps that need to be addressed in Ebola vaccine research

Despite promising advances, important scientific questions remain unanswered in the effort to develop a safe and effective Ebola vaccine, according to members of an international Ebola research consortium.

13 Aug 2018

FDA approves first oral medication for treatment of adults with Fabry disease

The U.S. Food and Drug Administration today approved Galafold (migalastat), the first oral medication for the treatment of adults with Fabry disease.

10 Aug 2018

New type of bed net could prevent millions of malaria cases, shows research

A new type of bed net could prevent millions of cases of malaria, according to new research published in The Lancet today (10 August).

10 Aug 2018

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.

10 Aug 2018

Crowdsourcing of algorithms enables epileptic seizure prediction in wide range of patients

A study by University of Melbourne researchers reveals clinically relevant epileptic seizure prediction is possible in a wider range of patients than previously thought, thanks to the crowdsourcing of more than 10 000 algorithms worldwide.

10 Aug 2018

New combination therapy for cancer cells could soon be a reality

A new cancer therapy using nanoparticles to deliver a combination therapy direct to cancer cells could be on the horizon, thanks to research from the University of East Anglia.

From Precision NanoSystems Inc. 10 Aug 2018

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Researchers study use of MRI-guided focused ultrasound to open blood-brain barrier

In the first such clinical trial in the United States, physician-scientists with the University of Maryland School of Medicine are investigating the use of MRI-guided focused ultrasound to open the blood-brain barrier.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Older kidney disease patients on dialysis have higher dementia risk

Older kidney disease patients who are sick enough to require the blood-filtering treatment known as dialysis are at high risk of dementia, including Alzheimer's disease, according to a study led by scientists at Johns Hopkins Bloomberg School of Public Health.

9 Aug 2018

New study investigates whether nicotine could slow memory loss

Can nicotine slow or stop memory loss in people experiencing mild memory problems, or mild cognitive impairment? A new study being conducted at Georgetown University Medical Center aims to find out.

9 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Responsive parenting intervention promotes healthy weight in young children

An intervention designed to promote healthy growth that taught first-time moms how to respond with age-appropriate responses to their babies' needs resulted in children having lower body mass indexes when they were three years old.

9 Aug 2018

Study identifies distinct genetic mutations in appendix cancer that may impact treatment

The rarity of appendix cancer, accounting for less than 1 percent of tumors that originate in the gastrointestinal tract, and the lack of scientific data for this disease means that current treatment guidelines recommend applying therapies to people with appendix cancer that are intended for those with colon cancer.

9 Aug 2018

Electing to induce labor at 39 weeks reduces the need for C-section

Inducing labor in healthy women at 39 weeks into their pregnancy reduces the need for cesarean section and is at least as safe for mother and baby as waiting for spontaneous labor.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

Clinical Trial News and Research

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

New intervention to reduce risk of HIV in young transgender women

Researchers discover secret communication hotline between breast cancers and normal cells

Experts highlight key knowledge gaps that need to be addressed in Ebola vaccine research

FDA approves first oral medication for treatment of adults with Fabry disease

New type of bed net could prevent millions of malaria cases, shows research

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

Crowdsourcing of algorithms enables epileptic seizure prediction in wide range of patients

New combination therapy for cancer cells could soon be a reality

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

Researchers study use of MRI-guided focused ultrasound to open blood-brain barrier

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

Older kidney disease patients on dialysis have higher dementia risk

New study investigates whether nicotine could slow memory loss

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

Responsive parenting intervention promotes healthy weight in young children

Study identifies distinct genetic mutations in appendix cancer that may impact treatment

Electing to induce labor at 39 weeks reduces the need for C-section

Scientists identify drug that could reverse pulmonary arterial hypertension

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

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