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UA scientists aim to identify drug targets for rare pediatric cancer

Rhabdomyosarcoma is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes).

1 Nov 2018

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

Today, the U.S. Food and Drug Administration permitted marketing, with special controls, of the 23andme Personal Genome Service Pharmacogenetic Reports test as a direct-to-consumer test for providing information about genetic variants that may be associated with a patient's ability to metabolize some medications to help inform discussions with a health care provider.

1 Nov 2018

Genetic testing and breakthrough therapies may transform diagnosis, care of neuromuscular disease

A new report funded by the Muscular Dystrophy Association and released by the IQVIA Institute for Human Data Science indicates that genetic testing and breakthrough therapies will transform the diagnosis and care of neuromuscular disease within the next decade.

31 Oct 2018

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine.

31 Oct 2018

Growth of genomic databases hinders efforts to identify bacteria

There are many ways to slice and dice genomic data to identify a species of bacteria, or at least find its close relatives. But fast techniques to sequence genomes have flooded the public databases and in a biased fashion, containing lots of genomic data about some species and not enough about others, according to a Rice University computer scientist.

31 Oct 2018

Top researchers call for unified standards in 3D genome and epigenetic data

Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease.

30 Oct 2018

Using genome editing to prevent sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people.

30 Oct 2018

Individual cells within the same heart cope differently with high blood pressure, study shows

Individual cells within the same heart cope differently with high blood pressure, according to a study in human cells and mice by a team of cardiologists and computational biologists at the University of Tokyo.

30 Oct 2018

Monkeys infected with Zika virus points to a sylvatic transmission cycle

Zika virus has been detected in dead monkeys found in Brazil near São José do Rio Preto, São Paulo State, and Belo Horizonte, Minas Gerais.

30 Oct 2018

NEC and Transgene sign MOU for strategic collaboration aimed at treating solid cancers

NEC Corporation and Transgene today announced the signing of a Memorandum of Understanding for a strategic collaboration aimed at the treatment of solid cancers.

30 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

New method increases virus production in cells to generate more vectors for gene transfer

Researchers at Tokyo Medical and Dental University have established a method to increase the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes into cells

29 Oct 2018

Scientists discover kill code in all cells that can be triggered to destroy cancer

Researchers have discovered a kill code present within every cell of the body in the form of microRNAs that can cause cancerous cells to self-destruct

29 Oct 2018

Study finds kill code mechanism embedded in every cell to extinguish cancer

A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study. As soon as the cell's inner bodyguards sense it is mutating into cancer, they punch in the kill code to extinguish the mutating cell.

29 Oct 2018

Barcelona researchers win one of the most prestigious EU grants to study CLL

The European Research Council today announced the results of the 2018 Synergy Grants call for proposals. The aim of Synergy Grants is to address ambitious research questions that can only be answered by the coordinated work of a small group of two to four principal investigators and their teams, bringing together their complementary skills, knowledge and resources.

26 Oct 2018

Polygenic screening could inform breast cancer risk in female survivors of pediatric cancer

A combined evaluation of common variants with small effects and rare predisposing mutations among young female childhood cancer survivors may further stratify this high-risk population for subsequent breast cancer risk.

26 Oct 2018

Study provides complete picture of genetic breast cancer susceptibility among pediatric cancer survivors

St. Jude Children's Research Hospital researchers have evidence that common genetic variations can help to identify pediatric cancer survivors who are at increased risk for developing breast cancer while relatively young. The findings appear today in the journal Clinical Cancer Research.

26 Oct 2018

Researchers identify genes responsible for sun sensitivity and skin cancer vulnerability

Research carried out at the Health Sciences department of the Universitat Jaume I of Castellón, Spain, has identified the genes responsible for sun sensitivity and skin cancer vulnerability.

25 Oct 2018

Identifying ways to improve existing guidelines for ethical human-animal chimera research

In Greek mythology, a chimera is a figure with the head of a lion, the body of a goat, and the tail of a serpent. But the concept is not entirely imaginary.

25 Oct 2018

'Cancer Gene Census' could help find drug targets and design treatments

Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the "Cancer Gene Census". Describing all genes strongly implicated in causing cancer, the Census also describes how they function across all forms of this disease.

25 Oct 2018

Genome News and Research

UA scientists aim to identify drug targets for rare pediatric cancer

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

Genetic testing and breakthrough therapies may transform diagnosis, care of neuromuscular disease

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

Growth of genomic databases hinders efforts to identify bacteria

Top researchers call for unified standards in 3D genome and epigenetic data

Using genome editing to prevent sudden cardiac death

Individual cells within the same heart cope differently with high blood pressure, study shows

Monkeys infected with Zika virus points to a sylvatic transmission cycle

NEC and Transgene sign MOU for strategic collaboration aimed at treating solid cancers

Insights into tumor initiation pave way for new skin cancer treatments

New method increases virus production in cells to generate more vectors for gene transfer

Scientists discover kill code in all cells that can be triggered to destroy cancer

Study finds kill code mechanism embedded in every cell to extinguish cancer

Barcelona researchers win one of the most prestigious EU grants to study CLL

Polygenic screening could inform breast cancer risk in female survivors of pediatric cancer

Study provides complete picture of genetic breast cancer susceptibility among pediatric cancer survivors

Researchers identify genes responsible for sun sensitivity and skin cancer vulnerability

Identifying ways to improve existing guidelines for ethical human-animal chimera research

'Cancer Gene Census' could help find drug targets and design treatments

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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