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Researchers discover relationship between TGFb signalling pathways and CXCR4 in HCC

Researchers from the Biological clues of the invasive and metastatic phenotype group of the Bellvitge Biomedical Research Institute (IDIBELL) led by Isabel Fabregat have discovered the relationship between the TGFb signalling pathways and CXCR4 in hepatocellular carcinoma (HCC) .

7 Nov 2013

New study could help lead to prevention and treatment of heart failure in diabetics

Researchers from the University of Texas Medical Branch at Galveston have discovered one of the pathogenic components of diabetes in the heart, as published in the Journal of Biological Chemistry.

7 Nov 2013

Buyang Huanwu Decoction regulates neural stem cell behavior in ischemic brain

The traditional Chinese medicine Buyang Huanwu Decoction has been shown to improve the neurological function of patients with stroke.

7 Nov 2013

Study: Increased duration of breastfeeding could be associated with decreased incidence of autism

In an article appearing in Medical Hypotheses on September 20, a New York-based physician-researcher from the Touro College of Osteopathic Medicine has called for the testing of umbilical cord blood for levels of a growth protein that could help predict an infant's propensity to later develop autism.

6 Nov 2013

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and Five Prime Therapeutics, Inc., a clinical-stage biotechnology company focused on discovering and developing novel protein therapeutics for cancer and inflammatory diseases, today announced an exclusive license agreement for human antibodies directed to an undisclosed target expressed on the surface of various types of cancers.

6 Nov 2013

Treadmill training improves functional recovery, neural plasticity after incomplete spinal cord injury

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection.

6 Nov 2013

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Kathleen Sakamoto, MD, PhD, and Irving Weissman, MD, of the Stanford University School of Medicine and Lucile Packard Children's Hospital, have received a $1.37 million grant from CureSearch for Children's Cancer to research the effects of an antibody that has been shown to be effective against human cancers in animal models.

5 Nov 2013

Effective strategy for noninvasive detection of cancer

Molecules that bind and illuminate proteins specific to tumor cells are key to detecting cancer as early as possible. The cyclooxygenase-2 enzyme is just such a protein, as the concentration of COX-2 is greater in cancer cells than in adjacent normal tissues.

5 Nov 2013

Linkam Scientific Instruments report the use of CMS196 for the imaging of mammalian cells at the London Research Institute, Cancer Research UK

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their innovative CMS196 cryo stage for the study of mammalian cells at the London Research Institute, Cancer Research UK.

From Linkam Scientific Instruments 5 Nov 2013

Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Whitehead Institute scientists report that the gene mutated in the rare hereditary disorder known as Birt-Hogg-Dub- cancer syndrome also prevents activation of mTORC1, a critical nutrient-sensing and growth-regulating cellular pathway.

5 Nov 2013

Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

Leicester scientists have mapped the "bouquet-like" structure of a key part of the body's immune system responsible for neutralising bacteria and viruses.

5 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

GeNeuro announced today that its GNbAC1 humanized monoclonal antibody was found to have a very good safety profile when administered to patients with relapsing and progressive forms of Multiple Sclerosis as part of a Phase 2a study.

4 Nov 2013

Research findings offer new therapeutic paradigm for periodontal disease

The red, swollen and painful gums and bone destruction of periodontal disease could be effectively treated by beckoning the right kind of immune system cells to the inflamed tissues, according to a new animal study conducted by researchers at the University of Pittsburgh.

4 Nov 2013

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Nov 2013

McMaster University researchers discover how metformin drug works on fat in the liver

About 120 million people around the world with Type 2 diabetes - and two million in Canada - take the drug metformin to control their disease.

4 Nov 2013

Experimental drug effective in treating patients with non-small cell lung cancer

An experimental cancer drug that has shown promise in the treatment of melanoma has also shown early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death among men and women worldwide.

4 Nov 2013

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Researchers at Chalmers University of Technology in Sweden, together with researchers at the Polish Wroclaw University of Technology, have made a discovery that may lead to the curing of diseases such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease (the so called mad cow disease) through photo therapy.

3 Nov 2013

Oncology drug development services: an interview with Dr. Jean-Pierre Wery, President of Crown Bioscience, Inc.

Crown serves pharmaceutical companies and biotech companies. We have two areas of focus: oncology and metabolic diseases. In the oncology space we focus on pre-clinical services. Essentially, we have all the tools to help our customers move from target discovery, target validation, to a clinical candidate.

31 Oct 2013

G Protein News and Research

Researchers discover relationship between TGFb signalling pathways and CXCR4 in HCC

New study could help lead to prevention and treatment of heart failure in diabetics

Buyang Huanwu Decoction regulates neural stem cell behavior in ischemic brain

Study: Increased duration of breastfeeding could be associated with decreased incidence of autism

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

Treadmill training improves functional recovery, neural plasticity after incomplete spinal cord injury

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Effective strategy for noninvasive detection of cancer

Linkam Scientific Instruments report the use of CMS196 for the imaging of mammalian cells at the London Research Institute, Cancer Research UK

Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Researchers identify factor that promotes metastasis of colon tumors

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

LMU researchers identify a factor that promotes metastasis of colon tumors

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

Research findings offer new therapeutic paradigm for periodontal disease

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

McMaster University researchers discover how metformin drug works on fat in the liver

Experimental drug effective in treating patients with non-small cell lung cancer

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Oncology drug development services: an interview with Dr. Jean-Pierre Wery, President of Crown Bioscience, Inc.

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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