Protein C News and Research

RSS

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers used a high throughput systems serology method to compare serum and CSF samples from SARS-CoV-2 infected individuals with and without long COVID symptoms to determine changes in the SARS-CoV-2 humoral immune responses.

15 Nov 2022

A novel mRNA-based vaccine candidate against the rabies virus

Scientists have developed a novel mRNA-based vaccine candidate against the rabies virus. The vaccine induces a strong antibody response and exhibits high protective efficacy against lethal rabies infection in mice and dogs. A full report about the vaccine has been published in the Virology Journal.

14 Nov 2022

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions - such as cell types or tissues.

14 Nov 2022

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age.

14 Nov 2022

Researchers provide new insights into the vexing process that makes HIV stealthy

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Older adults suffer from persistent cognitive impairment after recovery from SARS-CoV-2 infection

In addition to the respiratory and gastrointestinal symptoms that accompany COVID-19, many people with the virus experience short- and/or long-term neuropsychiatric symptoms, including loss of smell and taste, and cognitive and attention deficits, known as "brain fog."

14 Nov 2022

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages.

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

Researchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.

14 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

How air pollution affects the central nervous system over time

An article published in the journal Toxics describes how air pollutants adversely impact the human nervous system.

13 Nov 2022

Can monkeypox infection lead to myocarditis?

A recent study presents the first known case of myocarditis as a complication of monkeypox virus infection.

13 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Neuromedin U decreases food intake and raises energy expenditure in mice, not in rats

Our sensory urges ranging from anger to hunger are regulated by hormonal or neuronal signals. Often, these impulses appear as behavioral responses, evoked through complex biological reactions.

11 Nov 2022

Researchers discover new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

11 Nov 2022

Protein C News and Research

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

A novel mRNA-based vaccine candidate against the rabies virus

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

Researchers provide new insights into the vexing process that makes HIV stealthy

Novel drug could help to fight both COVID-19 and cancer

Older adults suffer from persistent cognitive impairment after recovery from SARS-CoV-2 infection

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

What is the role of macrophage origin, function, and heterogeneity in health and disease?

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

The viral fitness and antigenic relationship among Omicron sublineages

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

How mRNA vaccines work without an added adjuvant

How air pollution affects the central nervous system over time

Can monkeypox infection lead to myocarditis?

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Neuromedin U decreases food intake and raises energy expenditure in mice, not in rats

Researchers discover new antiviral compounds derived from two Korean native plants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News