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Researchers develop rapid method for identifying antibody-resistant SARS-CoV-2 mutants

Researchers in the United States have described a novel rapid method for identifying antibody-resistant mutants in SARS-CoV-2.

17 Mar 2021

Two mouthwashes disrupt COVID-19 virus under laboratory conditions

Researchers at Rutgers School of Dental Medicine have found evidence that two types of mouthwash disrupt the COVID-19 virus under laboratory conditions, preventing it from replicating in a human cell.

17 Mar 2021

CN Bio introduces the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 17 Mar 2021

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

The severity of COVID-19 among the residents of long-term care facilities (LTCFs) has been reported to be disproportionately high. Specifically, individuals residing in skilled nursing facilities (SNFs) are found to be the most severely affected, both in terms of morbidity and mortality, and are, thereby, listed for early COVID-19 vaccination. In comparison to the general population, SNF residents are more vulnerable, with a weak immune system.

17 Mar 2021

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

As vaccine efforts against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease, roll out in various countries, Moderna ups the game by testing its next-generation COVID-19 vaccine.

16 Mar 2021

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

Scientists in Colombia have identified a new highly divergent SARS-CoV-2 lineage with Spike substitutions L249S and E484K. These same mutations have convergently appeared in other mutant strains of the virus, most notably in variants of concern.

16 Mar 2021

Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Clinical trial begins to evaluate SENSE device’s ability to monitor intracranial hemorrhage

Sense Diagnostics, a medical technology company focused on improving outcomes for stroke and brain injury patients, announced the initiation of a multicenter pivotal trial to evaluate the safety and efficacy of a non-invasive brain scanner to monitor intracranial hemorrhage in an acute hospital setting.

16 Mar 2021

Janssen’s vaccine added to list of safe, effective tools against COVID-19

The World Health Organization (WHO) today listed the COVID-19 vaccine Ad26.COV2.S, developed by Janssen (Johnson & Johnson), for emergency use in all countries and for COVAX roll-out. The decision comes on the back of the European Medicines Agency (EMA) authorization, which was announced yesterday.

16 Mar 2021

New study tests how mutations in SARS-CoV-2 affect antibody neutralization

Using pseudoviruses with single amino acid substitutions, researchers found that mutations in SARS-CoV-2 reduce monoclonal antibody neutralization differently. However, convalescent sera samples did not lose neutralization potency many and were also effective against the B.1.1.7 (UK-derived) strain.

16 Mar 2021

Study compares antibiotic-only treatment versus surgery for acute uncomplicated appendicitis

An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

What is a protective neutralizing antibody titer against SARS-CoV-2 infection?

A new study describes a predictive model of protective immunity against SARS-CoV-2 infection that could help evolve optimal vaccination strategies to maintain protection and reduce the death rate.

15 Mar 2021

Why does convalescent plasma therapy for severe COVID-19 show mixed success?

A surprising new preprint, released on the medRxiv* server, suggests that the beneficial effects of convalescent plasma (CP) in this disease stem not only from the presence of neutralizing antibodies, but also the immunomodulatory effects of this plasma that shapes the host immune response.

15 Mar 2021

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

A recent study, currently available on the bioRxiv preprint server, indicates that a pair of dual-action monoclonal antibodies derived from an original 2003 SARS survivors could play an important role in the fight against coronavirus disease 2019 (COVID-19) due to their broadly neutralizing activity and the engagement of the immune system via effector function capabilities.

14 Mar 2021

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells.

14 Mar 2021

Researchers investigate digital contact tracing's ability to reduce the spread of COVID-19

Informing how COVID-19 response plans may incorporate digital contact tracing, a model of COVID-19 spread within a simulated French population found that if about 20% of the population adopted a contact tracing app on their smartphones, an outbreak could be reduced by about 35%. If more than 30% of the population adopted the app, the epidemic could be suppressed to manageable levels.

13 Mar 2021

Novel computer-guided design tool helps increase the efficiency of cell conversions

There is a great need to generate various types of cells for use in new therapies to replace tissues that are lost due to disease or injuries, or for studies outside the human body to improve our understanding of how organs and tissues function in health and disease.

13 Mar 2021

Cats with chronic kidney disease may help inform treatment for humans in future

The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans.

13 Mar 2021

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

In a study published in the journal Drugs, a researcher tackled the approval of Pfizer-BioNTech’s COVID-19 vaccine, which has now been used in many countries.

12 Mar 2021

Efficacy News and Research

Researchers develop rapid method for identifying antibody-resistant SARS-CoV-2 mutants

Two mouthwashes disrupt COVID-19 virus under laboratory conditions

CN Bio introduces the PhysioMimix™ OOC Multi-Organ Microphysiological System

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

Novel protein construct prevents lethal COVID-19 in mice

Clinical trial begins to evaluate SENSE device’s ability to monitor intracranial hemorrhage

Janssen’s vaccine added to list of safe, effective tools against COVID-19

New study tests how mutations in SARS-CoV-2 affect antibody neutralization

Study compares antibiotic-only treatment versus surgery for acute uncomplicated appendicitis

The role of nanotechnology in the fight against COVID-19

What is a protective neutralizing antibody titer against SARS-CoV-2 infection?

Why does convalescent plasma therapy for severe COVID-19 show mixed success?

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers investigate digital contact tracing's ability to reduce the spread of COVID-19

Novel computer-guided design tool helps increase the efficiency of cell conversions

Cats with chronic kidney disease may help inform treatment for humans in future

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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