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Tumour suppressor gene has greater anti-cancer activity than previously thought

New insight into the function of a gene important in the suppression of cancer is published today. Researchers at the National University of Ireland Galway have shown that the TP53 gene has even greater anti-cancer activity than previously thought.

22 Sep 2016

Novel immunotherapy shows promise against AML in clinical trial

A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place.

21 Sep 2016

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown.

21 Sep 2016

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, has awarded a 6-year, $4.4 million grant to St. Jude Children's Research Hospital and collaborators to improve the use of prescribed medication by sickle cell patients.

21 Sep 2016

BBI Solutions introduces novel conjugate blocking technology to improve performance of lateral flow immunoassays

BBI Solutions has launched Morffi, a novel conjugate blocking technology that enhances signal intensity and improves the sensitivity of lateral flow immunoassays, at the Lateral Flow Test Development seminar in Seattle, USA, on the 20th September.

21 Sep 2016

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division.

20 Sep 2016

Researchers propose new explanation for symptoms of fragile X syndrome

Until recently, scientists thought they understood one of the underlying causes of fragile X syndrome, the most common inherited cause of intellectual disability in the United States.

20 Sep 2016

Mice study finds new antiviral that can control flu infection

A molecule the body produces naturally in response to virus infection could be a viable flu treatment in the future, suggest researchers at the Francis Crick Institute in London.

20 Sep 2016

Researchers reveal previously unknown role of glutamate in neuromuscular development

For decades, scientists thought acetylcholine was the only neurotransmitter responsible for controlling how muscles and nerves are wired together during development.

20 Sep 2016

Clinical scientists find new way to treat hypertension

A team of clinical scientists at the University of Bristol have found a new way to treat high blood pressure (hypertension).

16 Sep 2016

Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

A potent cancer-fighting molecule in our cells can be reawakened by reducing levels of a protein - called SET - that's often found in excess in cancer cells, a new study from Columbia University's Herbert Irving Comprehensive Cancer Center has found.

15 Sep 2016

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system.

14 Sep 2016

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

A series of new studies led by scientists at The Scripps Research Institute and the International AIDS Vaccine Initiative describe a potential vaccination strategy to jump-start the selection and evolution of broadly effective antibodies to prevent HIV infection.

13 Sep 2016

New four-stranded version of DNA may hold key to development of targeted cancer therapies

Scientists have identified where a four-stranded version of DNA exists within the genome of human cells, and suggest that it may hold a key to developing new, targeted therapies for cancer.

13 Sep 2016

Triptolide molecule can turn into 'cruise missile' against cancer

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant.

9 Sep 2016

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them.

9 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Researchers discover how immune cells transition from silent to merciless killing machines

Neutrophils are the superheroes of the body's immune system. Normally mild-mannered, they travel through the bloodstream until they reach an emergency situation, such as a cut or infection, where they switch into battle-mode to engulf and destroy foreign invaders.

9 Sep 2016

Interactions between tumor cells and platelets could lead to cancer metastasis

Metastasis of cancer cells to sites distant from the primary tumor is the leading cause of cancer-related death, and there is growing evidence that platelets aid the dissemination of cancer cells.

9 Sep 2016

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania. The team published their work in Biological Psychiatry.

9 Sep 2016

Molecule News and Research

Tumour suppressor gene has greater anti-cancer activity than previously thought

Novel immunotherapy shows promise against AML in clinical trial

Bile acid transporter inhibitors can prevent NASH in mice, study shows

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

BBI Solutions introduces novel conjugate blocking technology to improve performance of lateral flow immunoassays

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

Researchers propose new explanation for symptoms of fragile X syndrome

Mice study finds new antiviral that can control flu infection

Researchers reveal previously unknown role of glutamate in neuromuscular development

Clinical scientists find new way to treat hypertension

Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

New four-stranded version of DNA may hold key to development of targeted cancer therapies

Triptolide molecule can turn into 'cruise missile' against cancer

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Researchers discover how immune cells transition from silent to merciless killing machines

Interactions between tumor cells and platelets could lead to cancer metastasis

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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