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Biodesix presents additional VeriStrat Phase III trial data at World Conference on Lung Cancer

Biodesix, Inc., a fully integrated molecular diagnostic company dedicated to personalizing medicine, today announced additional data from the Phase III clinical trial for its serum protein test, VeriStrat. Results were presented at the 15th World Conference on Lung Cancer in Sydney, Australia.

28 Oct 2013

International researchers identify 11 new genes linked to Alzheimer's disease

An international group of researchers has identified 11 new genes that offer important new insights into the disease pathways involved in Alzheimer's disease. The highly collaborative effort involved scanning the DNA of over 74,000 volunteers-the largest genetic analysis yet conducted in Alzheimer's research-to discover new genetic risk factors linked to late-onset Alzheimer's disease, the most common form of the disorder.

28 Oct 2013

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes.

28 Oct 2013

Rutgers scientists provide new information about rare genetic childhood disorder

Scientists at Rutgers University studying the cause of a rare childhood disease that leaves children unable to walk by adolescence say new findings may provide clues to understanding more common neurodegenerative diseases like Alzheimer's and Parkinson's and developing better tools to treat them.

28 Oct 2013

‘Distinct’ bipolar pathways revealed

A genetic analysis reported in Nature suggests two mechanisms that could lead to bipolar disorder.

25 Oct 2013

Hopes Raised For Early Pancreatic Cancer Detection

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25 Oct 2013

Research brings hope of new treatment for asthma patients resistant to corticosteroids

New research from Japan brings hope of a new treatment for asthma patients resistant to corticosteroids. In a study published today in the journal Nature Communications, researchers from the RIKEN Center for Integrative Medical Sciences and Keio University in Japan report that a type of lymphocytes called natural helper ells plays a critical role in corticosteroid resistance and demonstrate that the anti-psychotic drug Pimozide can be used to overcome resistance to steroids in severe asthma patients.

25 Oct 2013

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University. "Because they also lower cholesterol levels, they are extensively used in the food industry and as dietary supplements."

25 Oct 2013

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Nanyang Technological University (NTU) today launched a new electron microscopy lab led by world renowned scientist Professor Daniela Rhodes. Named the NTU Cryo-Electron Microscopy Laboratory, it is also the world's first university research facility to be equipped with an advanced cryo transmission electron microscope fitted with the latest detector/camera ten times more sensitive than a regular electron microscopy camera.

25 Oct 2013

New strategy could lead researchers to rapidly detect nutritional deficiencies

Johns Hopkins researchers have demonstrated that levels of certain proteins in the bloodstream may be used to estimate levels of essential vitamins and minerals without directly testing for each nutritional factor.

25 Oct 2013

"One-two punch" disables tumors' defenses

An aggressive form of breast cancer known as "triple negative" is very difficult to treat: Chemotherapy can shrink such tumors for a while, but in many patients they grow back and gain resistance to the original drugs.

25 Oct 2013

Whitehead Institute scientists identify novel Parkinson's disease drug target

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

25 Oct 2013

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

An international team of scientists has identified an association between heritable, rare mutations in the RINT1 gene and increased risk of early onset breast cancer, according to research reported today (Oct. 24) at the American Society of Human Genetics 2013 annual meeting in Boston.

25 Oct 2013

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

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24 Oct 2013

Common food additive can block new strain of avian influenza virus

A common food additive can block a deadly new strain of avian influenza virus from infecting healthy cells, report researchers at the University of Illinois at Chicago College of Medicine in the online journal, PLOS ONE.

24 Oct 2013

Study shows plant sterols appear to prevent onset of Alzheimer's disease

It's no secret that many of the phytochemicals in fruit and vegetables have a positive effect on our health. For instance, plant sterols (also known as phytosterols) help to lower cholesterol levels. According to a new study by researchers at Saarland University, they also appear to prevent the onset of Alzheimer's disease.

24 Oct 2013

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made.

24 Oct 2013

Activation mechanism of protective protein in ocular lens resolved

The lens of the human eye is made up of a highly concentrated protein solution that imparts the eye its high refractive power. Yet, despite this high protein content the ocular lens must remain clear and transparent.

24 Oct 2013

Diffregen awarded SBIR Phase 1 grant to advance Angiocidin towards human clinical trials

Diffregen LLC, a Temple University startup company, has been awarded a small business innovation research Phase 1 grant by the National Cancer Institute to advance Angiocidin, a university-created therapeutic to treat acute myeloid leukemia, to the doorstep of human clinical trials.

24 Oct 2013

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Acute dendritic leukaemia is a rare type of leukaemia, but one with the worst prognosis-the average patient survival rate is just 12-14 months-that is difficult to treat. Juan Cruz Cigudosa's team, from the Spanish National Cancer Research Centre's Molecular Cytogenetics Group, has for the first time sequenced the exome -the coding, or protein-generating, regions of the genome- of dendritic cell leukaemia.

24 Oct 2013

G Protein News and Research

Biodesix presents additional VeriStrat Phase III trial data at World Conference on Lung Cancer

International researchers identify 11 new genes linked to Alzheimer's disease

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

Rutgers scientists provide new information about rare genetic childhood disorder

‘Distinct’ bipolar pathways revealed

Hopes Raised For Early Pancreatic Cancer Detection

Research brings hope of new treatment for asthma patients resistant to corticosteroids

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

New strategy could lead researchers to rapidly detect nutritional deficiencies

"One-two punch" disables tumors' defenses

Whitehead Institute scientists identify novel Parkinson's disease drug target

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

Common food additive can block new strain of avian influenza virus

Study shows plant sterols appear to prevent onset of Alzheimer's disease

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Activation mechanism of protective protein in ocular lens resolved

Diffregen awarded SBIR Phase 1 grant to advance Angiocidin towards human clinical trials

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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