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Damaging the tumor blood vessels could be new strategy to treat oral cancer

Researchers at Okayama University have recently published a study in Cells in which they reduced the size of oral cancer tumors by damaging the blood vessels surrounding the tumor cells.

17 Mar 2020

Changes in cellular degradation hubs can lead to cancer

A team of scientists at Uppsala University has revealed that alterations in cells’ lysosomes underly abnormal cell growth.

17 Mar 2020

Study shows how alterations in cellular degradation hubs can lead to cancer

Cancer cells grow and divide in an uncontrolled manner. A new study from Uppsala University now shows how alterations in a cell's degradation hubs, called lysosomes, can cause abnormal cell growth.

17 Mar 2020

Scientists engineer silkworms to produce different variants of adhesion molecules

Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

'Natural killer' cells could help stop progression of Parkinson's disease

Researchers at the University of Georgia's Regenerative Bioscience Center and their colleagues have found that "natural killer" white blood cells could guard against the cascade of cellular changes that lead to Parkinson's disease and help stop its progression.

16 Mar 2020

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells.

16 Mar 2020

Overview of prognostic and predictive factors in pancreatic cancer

Oncotarget Volume 11, Issue 10 reported that there are not standardized predictive biomarkers able to identify patients who benefit most from treatments.

13 Mar 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

Post-diagnosis disparities drive worse outcomes for Black and Hispanic children with brain cancer

Cancer researchers have known for years that Black and Hispanic patients have worse outcomes than their non-Hispanic White peers.

12 Mar 2020

Research shows how immune cells act to limit tumor development

How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating T lymphocytes, both locally and remotely.

12 Mar 2020

Understanding how cancer cells interact and collaborate to metastasize

Cancer cells are known to migrate and collaborate to form networks that function as conduits providing access to nutrients and blood vessels.

12 Mar 2020

Researchers uncover clues to how statins kill cancer cells

More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

12 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Blood test for microbial DNA could warn of cancer

A new study published in the journal Nature on March 11, 2020, could transform the currently held views on cancer causation and diagnosis. The researchers have come up with a new technique to detect the presence and type of cancer by looking at microbial DNA circulating in the blood of the person being screened.

11 Mar 2020