Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

German Research Foundation approves funding for Mainz study on cardiovascular disorders

The German Research Foundation has approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote the further study of the interrelations between the immune system and cardiovascular system disorders.

29 Jan 2013

Study examines how fear responses are learned, controlled and memorized

A rustle of undergrowth in the outback: it's a sound that might make an animal or person stop sharply and be still, in the anticipation of a predator. That "freezing" is part of the fear response, a reaction to a stimulus in the environment and part of the brain's determination of whether to be afraid of it.

29 Jan 2013

Coming out of the closet helps reduce depressive symptoms and allostatic load levels in LGBs

Lesbians, gays and bisexuals (LGBs) who are out to others have lower stress hormone levels and fewer symptoms of anxiety, depression, and burnout, according to researchers at the Centre for Studies on Human Stress (CSHS) at Louis H. Lafontaine Hospital, affiliated with the University of Montreal. Cortisol is a stress hormone in our body. When chronically strained, cortisol contributes to the 'wear and tear' exerted on multiple biological systems. Taken together, this strain is called "allostatic load".

29 Jan 2013

Dual-hormone artificial pancreas shows promise against type 1 diabetes

IRCM researchers, led by endocrinologist Dr. R-mi Rabasa-Lhoret, were the first to conduct a trial comparing a dual-hormone artificial pancreas with conventional diabetes treatment using an insulin pump and showed improved glucose levels and lower risks of hypoglycemia.

29 Jan 2013

Bone Medical announces initial findings from BN006 proof of concept RA study

Bone Medical Ltd, a biopharmaceutical company focused on the development of new medicines for musculoskeletal diseases, today announced initial findings from a proof of concept study of BN006, a treatment that it is developing for Rheumatoid Arthritis (RA) based on its Mozaic™ peptide discovery technology.

29 Jan 2013

Emotional stress can reduce prostate cancer drugs’ effectiveness

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients. A new study by researchers at Wake Forest Baptist Medical Center indicates that stress is not just an emotional side effect of the diagnosis; it also can reduce the effectiveness of prostate cancer drugs and accelerate the development of prostate cancer.

29 Jan 2013

Prediagnostic androgen level not linked to prostate cancer outcome

Low prediagnostic levels of circulating sex hormones are not associated with more aggressive disease in patients with prostate cancer, say US researchers.

28 Jan 2013

Lumpectomy plus radiation may provide better chance of survival than mastectomy in early breast cancer patients

A new analysis has found that lumpectomy plus radiation for early breast cancer may provide patients with a better chance of survival than mastectomy. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the results provide confidence in the efficacy of breast-conserving treatments even among patients with aggressive, early disease.

28 Jan 2013

Less invasive treatment can provide superior survival to mastectomy in early stage breast cancer

Patients with early stage breast cancer who are treated with lumpectomy plus radiation have a better chance of survival compared with those who undergo mastectomy, according to Duke Medicine research.

28 Jan 2013

FDA approves Takeda’s NESINA, OSENI and KAZANO for treatment of type 2 diabetes

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc. today announced that the United States (U.S.) Food and Drug Administration (FDA) has approved NESINA (alogliptin) and the fixed-dose combination (FDC) therapies OSENI (alogliptin and pioglitazone) and KAZANO (alogliptin and metformin HCl) for the treatment of type 2 diabetes in adults as adjuncts to diet and exercise.

28 Jan 2013

Study shows how GATA3 protein acts downstream biochemically to prevent breast cancer metastasis

The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries point to possible targets for therapy.

28 Jan 2013

Behavioral stress accelerates prostate cancer development in mice

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer.

28 Jan 2013

African-American women who reported childhood abuse had greater risk of uterine fibroids

According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared with women who had no such abuse history.

25 Jan 2013

High blood calcium levels may predict ovarian cancer

A new study from Wake Forest Baptist Medical Center is the first to report that high blood calcium levels might predict of ovarian cancer, the most fatal of the gynecologic cancers.

25 Jan 2013

Findings could help explain prevalence of urinary tract infections in post-menopausal women

Researchers from Washington University School of Medicine, St. Louis, show that reservoirs of uropathogenic E. coli within the bladder exist in higher numbers post-menopause than pre-menopause in a mouse model, a finding that could help explain the greater prevalence of urinary tract infections in post-menopausal women.

25 Jan 2013

Mice exposed to BPA exhibit spontaneous activity, have leaner body mass

Female mice exposed to Bisphenol A through their mother's diet during gestation and lactation were found to be hyperactive, exhibit spontaneous activity and had leaner body mass than those not exposed to the chemical, researchers at the University of Michigan School of Public Health have discovered.

25 Jan 2013

Keeping active can slow down memory loss in Alzheimer's patients

Keeping active can slow down the progression of memory loss in people with Alzheimer's disease, a study has shown.

25 Jan 2013

Biomedical engineers identify natural switch that controls breast cancer metastasis

With a desire to inhibit metastasis, Cornell biomedical engineers have found the natural switch between the body's inflammatory response and how malignant breast cancer cells use the bloodstream to spread.

24 Jan 2013

NIH panel recommends name change for polycystic ovary syndrome

An independent panel convened by the National Institutes of Health has concluded that the name of a common hormone disorder in women, polycystic ovary syndrome (PCOS), causes confusion and is a barrier to research progress and effective patient care. The current name focuses on a criterion - ovarian cysts - which is neither necessary nor sufficient to diagnose the syndrome.

24 Jan 2013

Hormone News and Research

Further Reading

Mice with mitochondrial mutation live longer, have less fat

German Research Foundation approves funding for Mainz study on cardiovascular disorders

Study examines how fear responses are learned, controlled and memorized

Coming out of the closet helps reduce depressive symptoms and allostatic load levels in LGBs

Dual-hormone artificial pancreas shows promise against type 1 diabetes

Bone Medical announces initial findings from BN006 proof of concept RA study

Emotional stress can reduce prostate cancer drugs’ effectiveness

Prediagnostic androgen level not linked to prostate cancer outcome

Lumpectomy plus radiation may provide better chance of survival than mastectomy in early breast cancer patients

Less invasive treatment can provide superior survival to mastectomy in early stage breast cancer

FDA approves Takeda’s NESINA, OSENI and KAZANO for treatment of type 2 diabetes

Study shows how GATA3 protein acts downstream biochemically to prevent breast cancer metastasis

Behavioral stress accelerates prostate cancer development in mice

African-American women who reported childhood abuse had greater risk of uterine fibroids

High blood calcium levels may predict ovarian cancer

Findings could help explain prevalence of urinary tract infections in post-menopausal women

Mice exposed to BPA exhibit spontaneous activity, have leaner body mass

Keeping active can slow down memory loss in Alzheimer's patients

Biomedical engineers identify natural switch that controls breast cancer metastasis

NIH panel recommends name change for polycystic ovary syndrome

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