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Modified Cdk5 enzyme triggers damage to nerve cell connections in human Alzheimer's brains

Alzheimer's disease is characterized by abnormal proteins that stick together in little globs, disrupting cognitive function. These sticky proteins are mostly made up of beta-amyloid peptide. A better understanding of these proteins, how they form, and how they affect brain function will no doubt improve the diagnosis and treatment of Alzheimer's disease.

16 Aug 2011

New pathway for type 2 diabetes

Newly diagnosed type 2 diabetics tend to have one thing in common: obesity. Exactly how diet and obesity trigger diabetes has long been the subject of intense scientific research.

16 Aug 2011

Fat interferes with body's sugar sensors to trigger type 2 diabetes

Researchers from the United States have identified how a high-fat diet can trigger type 2 diabetes, in experiments on mice and human tissue. They reveal in their study published in the journal Nature Medicine that fat interferes with the body's sugar sensors. The authors add that deeper understanding of the processes involved could help them develop a cure.

15 Aug 2011

Caffeine can treat postdural puncture headaches

People who suffer headaches after a spinal tap might have a relatively simple way to ease the painful throb: a caffeine tablet.

11 Aug 2011

FDA approves Gilead's Complera for treatment of HIV-1 infection

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Complera, a complete single-tablet regimen for the treatment of HIV-1 infection in treatment-naïve adults.

11 Aug 2011

Aeras, OETC announce initiation of new TB vaccine Phase IIb trial in patients with HIV

Aeras and the Oxford-Emergent Tuberculosis Consortium (OETC) announce today the start of a Phase IIb proof-of-concept efficacy trial of a new investigational tuberculosis (TB) vaccine that involves people living with the human immunodeficiency virus.

11 Aug 2011

Modified spider-silk proteins for nonviral gene delivery

Genetically engineered spider silk could help overcome a major barrier to the use of gene therapy in everyday medicine, according to a new study that reported development and successful initial laboratory tests of such a material. It appears in ACS' journal Bioconjugate Chemistry.

11 Aug 2011

Can a robot cure cancer?

The Lowy Cancer Research Centre at the University of New South Wales is hosting a select group of high school students and a pair of potentially cancer-curing robots tomorrow ( Friday 12th August) as a curtain raiser for National Science Week, with lab tours led by world-class scientists from Children’s Cancer Institute Australia (CCIA).

10 Aug 2011

Current Medical Research & Opinion publishes new data on EVISTA for postmenopausal osteoporosis

Eli Lilly and Company today announced that data on EVISTA® (raloxifene HCl tablets) therapy for more than three years was published online in Current Medical Research & Opinion.

10 Aug 2011

Flatworms provide new insight into organ regeneration, evolution of mammalian kidneys

Our bodies are perfectly capable of renewing billions of cells every day but fail miserably when it comes to replacing damaged organs such as kidneys. Using the flatworm Schmidtea mediterranea-famous for its capacity to regrow complete animals from minuscule flecks of tissue-as an eloquent example, researchers at the Stowers Institute for Medical Research demonstrated how our distant evolutionary cousins regenerate their excretory systems from scratch.

10 Aug 2011

Nottingham researchers to develop new early warning system for Alzheimer's

Researchers at The University of Nottingham have been awarded £670,000 to develop a new early warning system for Alzheimer's disease.

9 Aug 2011

Pfizer, UC San Diego sign research agreement to drive innovation in drug discovery

In an innovative collaboration designed to speed the process of drug discovery, Pfizer, Inc. and the University of California, San Diego Health Sciences announced today that UC San Diego has joined the ranks of other top-tier life science research institutions across the country as part of Pfizer's Centers for Therapeutic Innovation.

9 Aug 2011

New study focuses on Anopheles gambiae to prevent spread of malaria

A female mosquito cannot tell if the male that she has mated with is fertile or 'spermless' and unable to fertilise her eggs, according to a new study from scientists at Imperial College London.

9 Aug 2011

Researchers identify new source for sexual problems in middle-aged, older men

Researchers have found a potential new source for sexual problems among middle-aged and older men: the relationships between their female partners and the men's closest friends.

9 Aug 2011

Providers, patients worry about debt deal

Though the initial phase of the debt deal doesn't include immediate provider cuts, analysts say the next phase — the work of the 'super committee' — could make significant reductions in spending for entitlements like Medicare and Medicaid. Even some elements of the health law and scientific research could be on the chopping block.

6 Aug 2011

Novel studies explore new targets to prevent spread of breast cancer

Research into new methods to prevent and slow metastatic breast cancer will be presented this week at the Era of Hope conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program.

5 Aug 2011

European Union grant to support clinical research and education at ICRC

Mayo Clinic will receive $10 million in research funding from the European Union (EU) as part of a $220 million grant to its collaborator, the St. Anne's University Hospital in Brno, the Czech Republic.

5 Aug 2011

Innovative delivery systems and methods to treat breast cancer

In their lifetime, women have more than a 12 percent risk of being diagnosed with breast cancer. 1 This week, research on novel approaches to breast cancer treatment is being presented at the Era of Hope (EOH) conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program (BCRP).

4 Aug 2011

Conference to discuss novel studies that address how inherited genes cause breast cancer

A woman's ethnicity as well as her genetic makeup are two of the main risk factors for hereditary breast cancer. Research into understanding and treating hereditary breast cancer will be presented today at the Era of Hope conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program.

4 Aug 2011

W.M. Keck Foundation awards Jefferson scientists with $1M medical research grant

Scientists at Thomas Jefferson University have been awarded a $1 million medical research grant from the W.M. Keck Foundation for an ambitious project looking at the little explored 98 percent of the human genome and what role it may play in the onset and progression of diseases.

4 Aug 2011