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Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

11 Aug 2016

Researchers uncover one way breast cancer tumors resist vital medication

A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication.

11 Aug 2016

MPFI researchers induce and visualize formation of new synapses in real time in live animals

The formation of excitatory and inhibitory synapses between neurons during early development gives rise to the neuronal networks that enable sensory and cognitive functions in humans.

11 Aug 2016

Scientists provide new insights into workings of cancer-linked potassium channel

Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance.

11 Aug 2016

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cancer Discovery.

11 Aug 2016

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.

11 Aug 2016

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

A novel PET radiotracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital is able for the first time to reveal epigenetic activity - the process that determines whether or not genes are expressed - within the human brain.

11 Aug 2016

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

A method for "silencing" RNA that emerged from a University of Wisconsin-Madison spinoff company is in clinical trials in Europe, Asia and the United States against hepatitis B, an infection that can destroy the liver.

11 Aug 2016

New study suggests increased levels of hypocretin in the brain may play role in cocaine addiction

A new study from scientists at The Scripps Research Institute, funded by the National Institutes of Health's National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, suggests that increased levels of a molecule in the brain, called hypocretin, may contribute to cocaine addiction.

10 Aug 2016

Penn study sheds light on role of essential compound in maintaining optimal muscle function

Maintaining proper levels of an essential helper molecule is crucial for optimal muscle function, according to a study led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2016

SBP researchers discover potential drug target for treatment of type 2 diabetes

Researchers at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new potential target for drugs to prevent type 2 diabetes. A paper published today in the Journal of Clinical Investigation shows that blocking a cellular glucose sensor in muscle improves insulin responsiveness.

10 Aug 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

TSRI scientists zoom in to view how experimental therapy ZMapp targets Ebola virus

Scientists at The Scripps Research Institute now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus.

9 Aug 2016

CTCA at Western begins clinical trial for novel antibody to treat patients with advanced tumors

Cancer Treatment Centers of America at Western Regional Medical Center has dosed its first three patients as part of the launch of a Phase I clinical trial using a novel antibody to treat patients with advanced solid tumors.

8 Aug 2016

Immunotherapy innovations in oncology: an interview with Robert LaCaze

The body’s immune system is an excellent weapon against many diseases. For more than 100 years, immunology and immunotherapy have played an ever-increasing role in the understanding and treatment of cancer.

8 Aug 2016

Novel therapeutic strategy could target multiple aspects of Alzheimer's disease

Therapeutic strategies targeting Alzheimer's disease (AD)-related molecule β-amyloid (Aβ), Tau protein and BACE enzyme have been recently explored. However the therapeutic efficacy for a single target is not ideal.

8 Aug 2016

Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Tissue injury, such as occurs in response to a lack of oxygen, promotes an influx of immune cells to the site of damage.

5 Aug 2016

Botulinum toxins may cause remote effects by moving between neurons

The botulinum toxins are among the deadliest substances on Earth, and two specific toxins — including the popular drug Botox — have multiple uses for treating many neuromuscular conditions, including frown lines, disabling muscle spasms and migraine headaches.

5 Aug 2016

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Lymphoma is a cancer that affects lymphocytes, a type of white blood cell. The disease originates in a lymphoid organ (lymph node, spleen, or bone marrow) before spreading through the blood to infiltrate not only other lymphoid organs but also other tissues.

4 Aug 2016

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease.

4 Aug 2016

Molecule News and Research

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Researchers uncover one way breast cancer tumors resist vital medication

MPFI researchers induce and visualize formation of new synapses in real time in live animals

Scientists provide new insights into workings of cancer-linked potassium channel

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

New study suggests increased levels of hypocretin in the brain may play role in cocaine addiction

Penn study sheds light on role of essential compound in maintaining optimal muscle function

SBP researchers discover potential drug target for treatment of type 2 diabetes

Rare genetic variations linked to severe porphyria

TSRI scientists zoom in to view how experimental therapy ZMapp targets Ebola virus

CTCA at Western begins clinical trial for novel antibody to treat patients with advanced tumors

Immunotherapy innovations in oncology: an interview with Robert LaCaze

Novel therapeutic strategy could target multiple aspects of Alzheimer's disease

Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Botulinum toxins may cause remote effects by moving between neurons

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Research could help develop better therapies for new subtype of adenocarcinoma patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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