Genetic News and Research

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Scientists decipher comprehensive deer tick genome

A University of Maryland-led team of scientists has deciphered the first comprehensive, continuous genome for a parasite responsible for transmitting Lyme disease and other serious infections to hundreds of thousands of Americans yearly.

19 Jan 2023

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

Seeking to better understand more about the origins and movement of bubonic plague, in ancient and contemporary times, researchers at McMaster University, University of Sydney and the University of Melbourne, have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, creating the largest analysis of its kind.

19 Jan 2023

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Medical science has not yet been able to explain why the Epstein-Barr virus triggers infectious mononucleosis (IM) in some people with initial infections and not in others.

19 Jan 2023

Prevalence of antibiotic-resistant bacteria not higher among babies delivered by cesarean section

Imagine a horse race, where the winner takes it all and is awarded both food and protection against enemies. In the same way, bacteria compete with one another in the gut of newborn babies.

19 Jan 2023

Vaccinated women well protected against severe COVID-19 symptoms, complications during pregnancy

The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has today published, in the Lancet, the results of the '2022 INTERCOVID Study' conducted in 41 hospitals across 18 countries.

19 Jan 2023

Several genes and individual genetic variations associated with atrial fibrillation discovered

In the largest genetic study of heart arrhythmia to date, researchers led by Kazuo Miyazawa and Kaoru Ito at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the discovery of several genes and individual genetic variations that are associated with atrial fibrillation.

19 Jan 2023

Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

Partial genetic reprogramming might extend lifespan and reverse aging in old mice

Researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy.

19 Jan 2023

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

In this interview, News Medical spoke to Kate Lawrenson, Ph.D., about their latest research which detailed the molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

19 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less common ABO blood type, resulting in fewer donors.

18 Jan 2023

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers performed immunoglobulin (Ig)M and IgG epitope mapping against 487 SARS-CoV-2 peptides.

18 Jan 2023

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "Single-cell transcriptomics of peripheral blood in the aging mouse."

18 Jan 2023

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

Combination of multiple maps uncovers new genetic risk factor for AMD

Combining a map of gene regulatory sites with disease-associated loci has uncovered a new genetic risk factor of adult-onset macular degeneration (AMD), according to a new study publishing January 17th in the open access journal PLOS Biology by Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues.

18 Jan 2023

Epigenetic alternations associated with common genital malformation in male babies

An alarming increase in the occurrence of the most common genital malformation in male babies, hypospadias, is likely due to environmental factors, such as toxicant exposure, which alter epigenetic programming in a forming penis.

18 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

Dementia risk in women may be reduced by hormone replacement therapy

Women are at greater risk for dementia than men, probably because of waning estrogen levels following menopause. Estrogen is a key female hormone linked to reproductive, sexual, and neurological functions. A new study published in the journal Alzheimer's Research & Therapy examines how hormone replacement works in women with a high genetic risk for AD.

17 Jan 2023

Green living environments affect the composition of oligosaccharides in breastmilk

A new study conducted at the University of Turku, Finland, examined the association between the residential green environment and the individual oligosaccharide profile in the mother's breastmilk.

17 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

Genetic News and Research

Scientists decipher comprehensive deer tick genome

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Prevalence of antibiotic-resistant bacteria not higher among babies delivered by cesarean section

Vaccinated women well protected against severe COVID-19 symptoms, complications during pregnancy

Several genes and individual genetic variations associated with atrial fibrillation discovered

Understanding the mechanisms involved in heart disease and cancers

Partial genetic reprogramming might extend lifespan and reverse aging in old mice

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Immunological interactions between asthma, obesity, and the microbiota

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

Combination of multiple maps uncovers new genetic risk factor for AMD

Epigenetic alternations associated with common genital malformation in male babies

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Dementia risk in women may be reduced by hormone replacement therapy

Green living environments affect the composition of oligosaccharides in breastmilk

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Sequencing & Genomics: Elevating Science and Healthcare eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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