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Research findings may have implications for ALS and other neurological disorders

Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe.

4 Aug 2016

UTMB researchers unlock clues to understand signals that trigger labor and delivery process

In a normal full-term pregnancy, signals from the mature organs of the fetus and the aging placental membranes and placenta prompt the uterus' muscular walls to begin the labor and delivery process. It's still unclear how these signals accomplish this goal or how they reach from the fetal side to the maternal side.

3 Aug 2016

Scientists use new non-invasive PET scanning method to monitor hippocampal neurogenesis

Scientists from the RIKEN Center for Life Science Technology in Japan have used a new non-invasive PET scanning technique to obtain images of neuron proliferation in the subventricular zone and subgranular zone of the hippocampal dentate gyrus. Neurogenesis in the hippocampal dentate gyrus is known to be particularly affected by depression.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Excessive alcohol consumption linked to lower levels of nitric oxide in exhaled breath

A study led by researchers from Loyola Medicine and Loyola University Chicago has discovered a potential new health concern related to excessive alcohol consumption.

2 Aug 2016

New research opens door to influencing immune system

A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis.

2 Aug 2016

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production.

1 Aug 2016

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Insilico Medicine, Inc in collaboration with scientists from Atlas Regeneration, Inc, Vision Genomics, Inc and Howard University published two research papers on fibrosis in the lung and liver and fibrotic signatures in glaucoma.

30 Jul 2016

Tecan’s D300e Digital Dispenser offers quick liquid transfer down to picoliter levels

Tecan has introduced the D300e Digital Dispenser for applications that need faster, reliable dispensing down to picoliter volumes.

From Tecan 30 Jul 2016

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Quark Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office has granted a key patent covering the treatment of patients suffering from non-arteritic anterior ischemic optic neuropathy ("NAION") with the Company's ocular neuroprotectant QPI-1007.

30 Jul 2016

Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

New research from Roswell Park Cancer Institute offers clinicians treating patients with advanced liver cancer a way of determining which patients may benefit most from the targeted therapy sorafenib.

29 Jul 2016

Researchers identify reason why antidepressants take so long to work

An episode of major depression can be crippling, impairing the ability to sleep, work, or eat. In severe cases, the mood disorder can lead to suicide. But the drugs available to treat depression, which can affect one in six Americans in their lifetime, can take weeks or even months to start working.

29 Jul 2016

Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Researchers at UC Davis and Ionis Pharmaceuticals have developed a hybrid treatment that harnesses a monoclonal antibody to deliver antisense DNA to acute lymphoblastic leukemia (ALL) cells and that may lead to less toxic treatments for the disease.

29 Jul 2016

Research findings may offer new way to strengthen body’s natural defenses to battle pneumonia

A molecule being targeted in cancer is also critical for the immune system's ability to battle pneumonia, researchers at the University of Virginia School of Medicine have determined.

29 Jul 2016

Discovery of pain paradox paves way to new methods of pain control

A natural substance known to activate pain in the central nervous system has been found to have the opposite effect in other parts of the body, potentially paving the way to new methods of pain control.

28 Jul 2016

Updated guidelines for breast cancer increase number of patients who test HER2-positive

Changes to HER2 testing guidelines for breast cancer in 2013 significantly increased the number of patients who test HER2-positive, according to a new study by Mayo Clinic researchers published in the Journal of Clinical Oncology.

28 Jul 2016

New research elucidates details about architecture of synaptic transmission

For more than a century, neuroscientists have known that nerve cells talk to one another across the small gaps between them, a process known as synaptic transmission.

28 Jul 2016

Study sheds light on neuronal circuits during risky behavior

New research sheds light on what's going on inside our heads as we decide whether to take a risk or play it safe. Scientists at Washington University School of Medicine in St. Louis located a region of the brain involved in decisions made under conditions of uncertainty, and identified some of the cells involved in the decision-making process.

27 Jul 2016

Scientists discover modified human protein involved in Ebola virus replication

A newly identified requirement of a modified human protein in ebolavirus (EBOV) replication, may unlock the door for new approaches to treating Ebola.

26 Jul 2016

Molecule News and Research

Research findings may have implications for ALS and other neurological disorders

UTMB researchers unlock clues to understand signals that trigger labor and delivery process

Scientists use new non-invasive PET scanning method to monitor hippocampal neurogenesis

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Iron-containing catalysts can alter amino acids to help develop new drug candidates

Excessive alcohol consumption linked to lower levels of nitric oxide in exhaled breath

New research opens door to influencing immune system

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Tecan’s D300e Digital Dispenser offers quick liquid transfer down to picoliter levels

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

Researchers identify reason why antidepressants take so long to work

Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Research findings may offer new way to strengthen body’s natural defenses to battle pneumonia

Discovery of pain paradox paves way to new methods of pain control

Updated guidelines for breast cancer increase number of patients who test HER2-positive

New research elucidates details about architecture of synaptic transmission

Study sheds light on neuronal circuits during risky behavior

Scientists discover modified human protein involved in Ebola virus replication

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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