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Growing use of immunotherapy linked to increase in Medicare spending for outpatient terminal cancer care

A new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives were driven almost entirely by a type of treatment given to fewer than 1 in 5 patients.

27 Feb 2023

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

Eliminating animal milk alone from the diet of adults with eosinophilic esophagitis, or EoE, is as effective at treating the disease as eliminating animal milk plus five other common foods, a clinical trial funded by the National Institutes of Health has found.

27 Feb 2023

Definition of low-risk WNT-pathway medulloblastoma may need to be refined, say experts

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"

27 Feb 2023

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Large cell therapy trial in patients with chronic heart failure shows promising results

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

27 Feb 2023

Innovative methodology to detect viral RNA

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia, the Institute of Microelectronics of Barcelona and the Aragon Nanoscience and Materials Institute of Aragon —a joint institute of the CSIC and the University of Zaragoza— have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

27 Feb 2023

Personal use of psychedelics among therapists may be common, study finds

Whether personal use of psychedelics is appropriate among psychedelic therapists, a new study finds that it may be common.

27 Feb 2023

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Readers and tweeters urgently plea for a proper ‘role’ call in the ER

The story of one patient’s ER experience does not at all capture the complexities of an emergency department serving the needs of a stochastic patient population.

27 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

The natural history of tau accumulation and the impact of disease stage and reference region on the magnitude and effect size of regional change

Researchers performed serial tau imaging with 18F-MK6240 to detect tau accumulation in cognitively unimpaired beta-amyloid negative Alzheimer’s disease patients as well as those with mild cognitive impairment who were Aβ+ at baseline.

27 Feb 2023

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Researchers characterize COVID-19 symptom and viral load rebounds among untreated individuals with mild-to-moderate SARS-CoV-2 infection.

27 Feb 2023

Rapid AAV Titer for Bioprocessing in Gene Therapy

In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, while also discussing the various products Sartorius produces in order to aid in this.

From Sartorius 27 Feb 2023

Experts develop commercial formulation Campto for colorectal cancer

Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer.

25 Feb 2023

Viable treatment option for patients with advanced cervical cancer

A recent University of Kentucky Markey Cancer Center study suggests a new radiopharmaceutical compound may be a viable treatment option for patients with advanced cervical cancer.

25 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Therapy News and Research

Growing use of immunotherapy linked to increase in Medicare spending for outpatient terminal cancer care

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

Definition of low-risk WNT-pathway medulloblastoma may need to be refined, say experts

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Large cell therapy trial in patients with chronic heart failure shows promising results

Innovative methodology to detect viral RNA

Personal use of psychedelics among therapists may be common, study finds

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Researchers explore potential new target for cancer immunotherapy

Readers and tweeters urgently plea for a proper ‘role’ call in the ER

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

The natural history of tau accumulation and the impact of disease stage and reference region on the magnitude and effect size of regional change

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Rapid AAV Titer for Bioprocessing in Gene Therapy

Experts develop commercial formulation Campto for colorectal cancer

Viable treatment option for patients with advanced cervical cancer

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

UVA research provides new insight into common causes of vision loss

Palliative care not likely to reduce psychological distress

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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