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Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

A recent study identified six candidate mutations in the SARS-CoV-2 genome adaptive to animal hosts.

21 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Researchers designed an electrochemiluminescence-based serology test with remarkable sensitivity to precisely quantify the amounts of anti-RBD antibodies in individuals infected with SARS-CoV-2.

18 Feb 2022

ACE2 News and Research

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

N-glycosylation blockers reduce SARS-CoV-2 infection

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

The impact of SARS-CoV-2 on lipids

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

SARS-CoV-2 variants are evolving increased infectivity and antibody escape, studies say

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Children with severe COVID-19 show low mucosal neutralizing activity against SARS-CoV-2

Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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