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Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Humoral and cellular response to COVID-19 vaccines in patients with IBD

A new study published in the preprint server medRxiv* aimed to evaluate the humoral and cellular response to COVID-19 vaccine in patients with IBD undergoing biologic or immunomodulatory therapy.

17 Sep 2021

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

17 Sep 2021

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

To investigate the immune memory sustainability of SARS-CoV-2-specific B cells and T cells, stimulated by the inactivated vaccine, and the potential need for a third booster dose in healthcare workers (HCWs), a non-randomized trial was undertaken by researchers at Sun Yat-sen University in Guangzhou, China. the research is posted online on the medRxiv* preprint server.

17 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Flu shots and COVID-19 immunity

A new paper finds that the influenza vaccine may influence both the response to and incidence of infection by the SARS-CoV-2.

14 Sep 2021

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

14 Sep 2021

Low dose of Moderna COVID-19 vaccine generates durable immune response

A new study from La Jolla Institute for Immunology (LJI) scientists helps answer the question: how long does immunity against COVID-19 last in vaccinated people?

14 Sep 2021

A review of mesenchymal stem cell therapy for severe COVID-19

Researchers find that MSC treatment is highly tolerated and effective in reducing lung damage in COVID-19 patients and improving their chances of recovery.

13 Sep 2021

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

A new study reignites the debate regarding the therapeutic utility of convalescent plasma in treating others with the COVID-19.

7 Sep 2021

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

An intriguing new study reports a year-long study in patients with cMCADs from all over France.

7 Sep 2021

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

A team of scientists in Ireland recently identified certain immune markers that can predict the progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to severe coronavirus disease 2019 (COVID-19). Early detection of these predictive markers can facilitate therapeutic decision-making prior to peak severity.

7 Sep 2021

CD4 News and Research

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

T cell immunity induced after mild COVID could contribute to protection against re-infection

Humoral and cellular response to COVID-19 vaccines in patients with IBD

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

Flu shots and COVID-19 immunity

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

Low dose of Moderna COVID-19 vaccine generates durable immune response

A review of mesenchymal stem cell therapy for severe COVID-19

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

People living with HIV have higher risk of sudden cardiac death, finds study

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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