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A review of mesenchymal stem cell therapy for severe COVID-19

Researchers find that MSC treatment is highly tolerated and effective in reducing lung damage in COVID-19 patients and improving their chances of recovery.

13 Sep 2021

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

A new study reignites the debate regarding the therapeutic utility of convalescent plasma in treating others with the COVID-19.

7 Sep 2021

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

An intriguing new study reports a year-long study in patients with cMCADs from all over France.

7 Sep 2021

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

A team of scientists in Ireland recently identified certain immune markers that can predict the progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to severe coronavirus disease 2019 (COVID-19). Early detection of these predictive markers can facilitate therapeutic decision-making prior to peak severity.

7 Sep 2021

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Scientists from the National Institutes of Health, USA, have recently demonstrated the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based coronavirus disease 2019 (COVID-19) vaccines in hamsters.

6 Sep 2021

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

In a recent study, scientists attempt to understand persistent COVID-19 and its implications in patients with hematologic malignancies.

6 Sep 2021

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

6 Sep 2021

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy.

2 Sep 2021

Do kidney transplant recipients need a third booster dose of mRNA COVID-19 vaccine?

A team of researchers in France have observed that the “standard” 2 dose regimen for mRNA COVID-19 vaccines could provide adequate protection to only a few KTRs. It has also been shown in multiple studies that a considerable population of vaccinated KTRs were easily infected with SARS-CoV-2.

1 Sep 2021

Can barrier gestures be relaxed without causing a COVID-19 resurgence in France?

A new study focused on determining the magnitudes of a barrier gesture relaxation in France. Read more here.

1 Sep 2021

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

A recent study, available on the bioRxiv* preprint server, investigated the durability of cellular immune memory after mRNA vaccination against SARS-CoV-2 and whether booster jabs affect the durability of different immune response components. The study included testing for antibodies and cellular immune responses in covid patients and recovered individuals.

31 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Next-gen COVID vaccine to make persistent neutralizing antibodies

Presently, there is a need to develop improved versions of COVID-19 vaccines that are effective against the SARS-CoV-2 variants of concern (VOC) and can confer long-term protection. Considering the need of the hour, scientists from the University of Sydney in Australia have generated a new COVID-19 vaccine CoVac-II and evaluated its effect against COVID-19 strains. The findings from this study are published on the bioRxiv* preprint server while awaiting peer review.

30 Aug 2021

MS patients on anti-CD20 therapy have robust T cell responses to SARS-CoV-2 vaccination

Scientists have observed that MS patients exhibit a robust T cell response despite a reduced humoral response to COVID-19 vaccines. Read more here.

27 Aug 2021

Could soluble CD24 offer some hope against severe COVID-19?

A recent randomized phase III trial conducted by researchers at the Ohio State University, Columbus, OH, US, evaluated the impact of CD24Fc in severe COVID-19 patients and showed promising clinical efficacy. This study is available as a preprint on the medRxiv* server.

26 Aug 2021

CD4 News and Research

A review of mesenchymal stem cell therapy for severe COVID-19

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

People living with HIV have higher risk of sudden cardiac death, finds study

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Do kidney transplant recipients need a third booster dose of mRNA COVID-19 vaccine?

Can barrier gestures be relaxed without causing a COVID-19 resurgence in France?

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Next-gen COVID vaccine to make persistent neutralizing antibodies

MS patients on anti-CD20 therapy have robust T cell responses to SARS-CoV-2 vaccination

Could soluble CD24 offer some hope against severe COVID-19?

Analysis of antibody titer decay following vaccination or SARS-CoV-2 infection

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

Glycyrrhizic acid as a drug candidate for COVID-19

Industry Focus eBook - Cell biology (5th edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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