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Horizon Discovery announces full commercial licensing of GS knockout CHO K1 cell line to Glenmark

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation for cell line engineering, today announced the full commercial licensing to Glenmark Pharmaceuticals, a global innovative pharmaceutical company, of its gene-edited Glutamine Synthetase knockout Chinese Hamster Ovary K1 cell line. Terms of the agreement were based on stringent evaluation of the cell line by Glenmark to assess its suitability for adoption into the Company’s biomanufacturing processes.

From Revvity 30 Sep 2019

Johns Hopkins researchers link a gene to melanoma growth and spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3.

From Johns Hopkins Medicine 25 Sep 2019

Newly synthesized anticancer compound can block cancer signaling mechanism

Of the various different functions that proteins perform in a cell, a crucial one is the recognition and transmission of certain "signals," collectively referred to as signal transduction.

24 Sep 2019

Oxford Genetics unveils OXGENE brand

Oxford Genetics Ltd announces the launch of its brand OXGENE™. The new brand articulates the company’s powerful ability to combine highly innovative science with an engineering approach to custom solutions for biotechnology.

From OXGENE 11 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers at New York University Oral Cancer Center were awarded a $2.5 million grant (R01CA228525) from the National Cancer Institute, part of the National Institutes of Health, to study the role of artemin in oral cancer pain and growth.

5 Sep 2019

New model system uses red blood cells to study malaria invasion

Researchers at the University of Bristol and Imperial College London have established a new model system that uses red blood cells grown in the laboratory to study how malaria parasites invade red blood cells.

29 Aug 2019

Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife.

27 Aug 2019

Study uncovers potential new treatment approach for lung cancer

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway.

19 Aug 2019

Sartorius Stedim Biotech announces launch of new services for mammalian cell bank manufacturing

Sartorius Stedim Biotech (SSB), a leading partner of the biopharmaceutical industry, today announced the launch of new services for mammalian cell bank manufacture under GMP conditions.

From Sartorius 13 Aug 2019

Stimulating immune cells with nanosecond pulsed electric fields can cause them to respond

Nanosecond pulsed electric fields produce strong electrical effects by focusing a high powered electrical pulse over a very short period of time.

7 Aug 2019

Canine tumor appears immortal, spreads from dog to dog across all boundaries

A new study has revealed that the oldest and most widespread cancer cell line in the world is the contagious dog cancer called CTVT. This is among the few transmissible cancers. The canine transmissible venereal tumor (CTVT) has been found to cause sexually transmitted tumors in dogs for over 8,500 years.

2 Aug 2019

New leukemia treatment developed from common wild flower

Researchers have discovered how to turn a compound from a common wildflower called Feverfew into a new treatment for leukemia.

1 Aug 2019

Researchers identify chemical compounds that increase stability of haploid cell

Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic cells. Haploid cells are a powerful genetic tool to analyze gene function.

17 Jul 2019

Olympus Europe and Cytosurge join hands to accelerate drug development, single cell research

Olympus Europe and Cytosurge have partnered in order to accelerate common innovation of next-generation tools for single cell experiments and to expand the distribution of the versatile FluidFM BOT single cell research tool.

From Evident Corporation - Life Sciences 10 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

Researchers find possible counterpunch to drug resistance of melanoma

Researchers at Oregon State University and Oregon Health & Science University have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer.

19 Jun 2019

Researchers develop DNA nanorobots that target breast cancer cells

According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2).

17 Jun 2019

Study assesses potential negative effect of Ochratoxin A on embryonic development

The study shows that the presence of Ochratoxin A affects survival and decreases the proliferation of human cells in the embryonic phase

11 Jun 2019

Study investigates if remote ischemic preconditioning could be beneficial to the brain

What if wearing a blood pressure cuff could help prevent stroke? In a new study, people who restricted their blood flow by wearing inflated blood pressure cuffs on an arm and leg showed signs of more controlled blood flow to their brain, a process that could be protective if blood flow is more severely restricted in the event of a stroke, according at a study published in the May 29, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

30 May 2019