Chimeric Antigen Receptor News and Research

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For low-income drug users, Medi-Cal offers a fresh start

Breann Johnson stopped using heroin on Mother's Day this year, determined to end her 13-year addiction. Days later, she began three months of residential treatment in Riverside, Calif. — all paid for by California's Medicaid program.

8 Sep 2017

Check list to help people with diabetes prepare for Hurricane Irma

With Hurricane Irma fast approaching Florida, preparing for a disaster can feel overwhelming. But for people with diabetes, preparing for the worst is a matter of survival. Janis Roszler, LMFT, RD, LD/N, CDE, FAND, American Association of Diabetes Educator member, shares her checklist for staying safe.

8 Sep 2017

ASMR soundscape aids in longer, healthier sleep

AXA PPP healthcare has collaborated with ASMRtist WhispersRed in order to remaster its very own track, creating a new night sound that can induce relaxation, aiding in longer sleep duration and healthier sleep patterns.

7 Sep 2017

Scientists identify key molecule for neurotransmitter release in synapses

The contact areas between nerve cells are called synapses. What happens there lies at the heart of communication between nerve cells. Communication starts with the release of chemical messengers known as neurotransmitters at these synapses.

4 Sep 2017

Virginia Mason’s therapy car now licensed for commercial production, distribution to therapists anywhere

The therapy car invented at Virginia Mason to help orthopedic surgery patients practice the physical motions needed to get in and out of a real vehicle without falling is now licensed for commercial production and distribution to physical and occupational therapists anywhere in the world.

31 Aug 2017

Some thyroid cancer patients can safely delay surgery

Most people diagnosed with cancer want to start treatment as soon as possible, for fear that delaying care will allow their tumor to grow out of control.

31 Aug 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

New study reveals economic implications of shift in school start times in the U.S.

The RAND Corporation and RAND Europe have released the first-ever, state-by-state analysis (in 47 states) of the economic implications of a shift in school start times in the U.S., showing that a nationwide move to 8.30 a.m. could contribute $83 billion to the U.S. economy within a decade.

30 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

Pioneering cancer gene therapy gets green light — and $475,000 price tag

The country's first approved gene therapy — approved Wednesday to fight leukemia that resists standard therapies — will cost $475,000 for a one-time treatment, its manufacturer announced.

30 Aug 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases - including cancer, diabetes and HIV - faster and cheaper to develop, and more customizable.

30 Aug 2017

Prolonged sitting and TV watching linked to mobility disability risk in older adults

Older people who watched more than five hours of TV per day and reported three or fewer hours per week of total physical activity had more than a three-fold higher risk of being unable to walk or having difficulty walking at the end of an 8-year study.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017