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Tirzepatide reveals a brain signal that predicts returning food preoccupation

Researchers implanted electrodes in the human nucleus accumbens to track brain activity during severe food preoccupation in an individual taking tirzepatide. They found that a delta–theta biomarker disappeared during symptom-free periods and re-emerged weeks before relapse, suggesting a possible neural marker of vulnerability to dysregulated eating.

18 Nov 2025

Early immunotherapy shows higher response in advanced basal cell carcinoma

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center found that patients with advanced basal cell carcinoma (BCC) may benefit from receiving immunotherapy earlier in the course of treatment.

18 Nov 2025

Daily black cumin intake improves blood lipids and reduces obesity risk

Nigella sativa (black cumin), the spice that boosts the flavor of curries like korma and paneer also has another use: its seeds have long been used as a medicinal plant in traditional medicine for their antioxidant and anti-inflammatory effects.

18 Nov 2025

Yale study exposes unequal access to new medicines after clinical trials

A new study led by Yale's Jennifer Miller, PhD, found that medicines are not physically accessible in many of the countries where they are tested for FDA approval.

17 Nov 2025

Brain recordings reveal short-lived effects of tirzepatide on food cravings

A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brain's "reward center" thought to be involved in food noise – but only temporarily.

17 Nov 2025

UCI Health launches clinical trial to test investigational cell therapy for lupus

UCI Health has opened a clinical trial to test an investigational cell therapy for lupus with the potential to give patients long-term remission of symptoms.

17 Nov 2025

Researchers engineer a novel technique for guiding endoscopes to deep lung tumors

Researchers at The University of Osaka have engineered a novel technique, Balloon-Assisted Bronchoscope Delivery (BDBD), to guide endoscopes to small, early-stage lung cancers hidden deep within the periphery of the lungs.

17 Nov 2025

Low-glutamate diet improves migraine symptoms in veterans with Gulf War Illness

Veterans with Gulf War Illness experienced significant improvement in migraine symptoms after following a diet low in glutamate, a component of flavor enhancing food additives commonly found in processed foods, according to new research presented by Georgetown University and American University scientists.

17 Nov 2025

New therapy restores vision after stroke induced blindness

Each year, thousands of stroke survivors are left with hemianopia, a condition that causes loss of half of their visual field (the "vertical midline"). Hemianopia severely affects daily activities such as reading, driving, or just walking through a crowded space.

17 Nov 2025

Low-intensity noise therapy shows how tuning sound to the brain can ease tinnitus

LINTS, a non-masking low-intensity noise tuned to each patient’s tinnitus frequency, produced statistically significant but modest reductions in tinnitus burden in a phase II clinical trial. Improvements were confined to the treatment-only group, with high individual variability and strong dependence on precise acoustic fitting.

16 Nov 2025

Testing nicotinamide riboside as a potential aid for long COVID recovery

Chao-Yi Wu, PhD, OT, from the Department of Neurology and Edmarie Guzmán-Vélez, PhD, of the Department of Psychiatry at Mass General Brigham, are the lead and senior authors of a paper published in eClinicalMedicine, "Effects of Nicotinamide Riboside on NAD+ Levels, Cognition, and Symptom Recovery in Long-COVID: A Randomized Controlled Trial."

14 Nov 2025

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

Cardiologists recommend reassessing need for additional stents later

A blocked coronary artery causing an acute heart attack must be opened immediately with a stent procedure. However, if other coronary arteries also appear to be narrowed, it is safe to wait and treat those later. This approach cuts the number of stent procedures in half, according to cardiologists from Radboud university medical center, writing in The New England Journal of Medicine.

14 Nov 2025

Automated insulin delivery improves glucose control in pregnant women with Type 1 diabetes

An international study co-led by University of Calgary researchers has found new insulin delivery technology helps control glucose levels during pregnancy for those with Type 1 diabetes, which is crucial to the health of women and their newborns.

13 Nov 2025

New study identifies a "sweet spot" in clinical decision-making

Having more options is always better - until it's not. Doctors face this paradox daily when choosing treatment plans for patients, especially under the pressure of packed clinical schedules. Too few choices can limit care, but too many can lead to decision fatigue.

13 Nov 2025

Cellarity's AI model predicts drug-induced liver injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

13 Nov 2025

Research identifies factors for long-term myeloma remission

A new study from the Icahn School of Medicine at Mount Sinai helps explain why some people with multiple myeloma, a type of blood cancer, stay in remission for many years after receiving CAR T cell therapy, while others see their cancer return sooner.

13 Nov 2025

Empowering early detection of dementia with a dual approach involving AI and patient input

Few primary care practices are designed for the timely detection of Alzheimer's disease and related dementias. The limited time that primary care clinicians are able to spend with patients, the need to focus on the health problems which brought the patient to the clinic, as well as the stigma of Alzheimer's disease and dementia are major reasons for lack of recognition of the condition.

13 Nov 2025

New typhoid conjugate vaccine shows safety and strong immune response in Africa

PATH and EuBiologics Co., LTD are pleased to announce Phase 3 results from a clinical trial of a typhoid conjugate vaccine (TCV), EuTYPH-C Inj.® Multi-dose. EuTYPH-C Inj.®

12 Nov 2025

Single-dose malaria treatment using four drugs achieves high cure rates in clinical trial

Hundreds of malaria patients participating in a Phase 3 clinical trial in Gabon in West Africa were cured via a single dose of a treatment that utilizes four widely available malaria drugs, according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

12 Nov 2025