Immunoglobulin News and Research

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Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Researchers assessed the impact of BNT162b2 coronavirus disease 2019 (COVID-19) vaccination on antibody acquisition.

23 May 2022

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Resarchers discuss the ability of shark-derived antibodies to protect against multiple variants of SARS-CoV-2.

23 May 2022

Women who are pregnant or nursing should receive a COVID booster vaccination

In a recent study posted to the medRxiv* preprint server, researchers evaluated the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccination in nursing and pregnant women.

23 May 2022

Anti-SARS-CoV-2 titers predict COVID severity

A recent study published in the journal Viruses reported that antibody titers against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could serve as a marker for the severity of coronavirus disease 2019 (COVID-19).

22 May 2022

Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

Serologic response to SARS-CoV-2 may predict COVID-19 severity

A new study reported that antibody titers against SARS-CoV-2 could serve as a marker for the severity of COVID-19.

20 May 2022

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Researchers performed a molecular analysis of cross-reactive antibodies targeted against the receptor-binding domain of SARS-CoV-2 strains among the general population.

20 May 2022

NIH team documents various types of neuropathy after COVID vaccination

In a recent study posted to the medRxiv* preprint server, researchers investigated if coronavirus disease 2019 (COVID-19) vaccination could result in neuropathic symptoms.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Researchers evaluated the humoral and T lymphocyte immune responses against SARS-CoV-2 variants of concern among mild COVID-19 convalescent patients in South Australia.

19 May 2022

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Researchers developed an enzyme-linked immunosorbent assay to detect antibodies against SARS-CoV-2 in urine samples.

19 May 2022

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

In a recent study posted to the medRxiv* preprint server, researchers estimated the humoral immunity imparted by the two/three doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in solid organ transplant recipients (SOTRs).

18 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

Immunoglobulin News and Research

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Women who are pregnant or nursing should receive a COVID booster vaccination

Anti-SARS-CoV-2 titers predict COVID severity

Study outlines risk factors for autoimmune hepatitis after liver transplant

Serologic response to SARS-CoV-2 may predict COVID-19 severity

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

NIH team documents various types of neuropathy after COVID vaccination

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

Recombinant protein vaccine stands up to SARS-CoV-2 variants

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

Study explores neurologic complications in pediatric COVID-19 cases

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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