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Zebrafish reveal how two genes independently drive sensory organ regeneration

Researchers identified that two cyclin D genes, ccndx and ccnd2a, independently regulate distinct stem and progenitor cell populations during zebrafish sensory organ regeneration. The findings reveal that regeneration can proceed via alternative pathways even when one gene is disrupted, providing new insight into tissue repair mechanisms.

20 Jul 2025

Researchers honored for groundbreaking work in cancer neuroscience

The University of Virginia School of Medicine's Harald Sontheimer, PhD, and Stanford's Michelle Monje, MD, PhD, have received the 2025 International Prize in Translational Neuroscience from the Gertrud Reemtsma Foundation for their pioneering research in the emerging field of cancer neuroscience.

18 Jul 2025

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Research uncovers role of whole-genome doubling in ovarian cancer evolution

Research led by Memorial Sloan Kettering Cancer Center (MSK) is shedding new light on how ovarian cancer evolves - insights that could help researchers develop more effective treatment strategies.

17 Jul 2025

Research suggests a new strategy to improve blood flow to the brain to battle Alzheimer's

New University of Virginia School of Medicine research suggests an unexpected way doctors may be able to improve blood flow to the brain to battle Alzheimer's and other neurodegenerative diseases.

16 Jul 2025

Study reveals critical role of the extracellular matrix in neuroblastoma progression

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix.

16 Jul 2025

UK Biobank completes world's largest whole-body imaging project

In a remarkable achievement that is already impacting how we detect and diagnose disease, UK Biobank has completed the world's largest whole body imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers.

16 Jul 2025

Virtual eye clinics in shopping centers cut waiting times for routine appointments

Innovative virtual eye clinics in shopping centres could significantly reduce waiting times for routine eye appointments, UCL-led research suggests in a first-of-its-kind study.

15 Jul 2025

AI and eye scans reveal better way to predict risk from short-sightedness

A combination of routine eye scans and AI has created a powerful new way for measuring short-sightedness to better predict people's long-term risk of serious retinal damage, a new study suggests.

15 Jul 2025

ChatGPT matches radiologists in pancreatic cyst analysis

Artificial intelligence (AI) models such as ChatGPT are designed to rapidly process data. Using the AI ChatGPT-4 platform to extract and analyze specific data points from the Magnetic Resonance Imaging (MRI) and computed tomography (CT) scans of patients with pancreatic cysts, researchers found near-perfect accuracy when compared directly against the manual approach of chart review performed by radiologists, according to a study published in the Journal of the American College of Surgeons (JACS).

15 Jul 2025

New approach makes mismatched stem cell transplants safer for blood cancer patients

Advances in blood stem cell transplants now make it possible for people with blood cancers to get safe and effective "mismatched" transplants that will potentially cure their disease, new UVA Cancer Center research reveals. The advances will allow far more people to receive the lifesaving treatment.

15 Jul 2025

New cellular entry pathway improves gene therapy outcomes

Scientists from the Centenary Institute and the University of Sydney have made a landmark discovery that could lead to safer and more effective gene therapies for a range of serious genetic disorders including Duchenne muscular dystrophy, Pompe disease and hemophilia.

15 Jul 2025

Study validates stem cell models for neurological diseases

In a comprehensive Genomic Press perspective (peer-reviewed review) article, an international team of neuroscientists has outlined crucial validity standards that could transform how researchers use stem cell technology to study devastating brain disorders.

15 Jul 2025

Endocrine Society experts call for more widespread screening of primary aldosteronism

Endocrine Society experts encouraged more widespread screening for a common hormonal cause of high blood pressure known as primary aldosteronism in a new Clinical Practice Guideline released today.

14 Jul 2025

Many Americans turn to AI for health answers despite accuracy warnings

Traditionally, individuals asked health questions of their primary health care provider. Confidence in that provider as a source of trustworthy health information has been consistently high in recent years and was at 90% in April, according to survey data from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

14 Jul 2025

Dual targeting of lipid kinases offers hope against emerging viruses

Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid molecules in the body.

14 Jul 2025

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems.

14 Jul 2025