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TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

A new model, TxGNN, revolutionizes zero-shot drug repurposing by predicting treatments for diseases with no known therapies, offering improved accuracy and trust via interpretable AI explanations.

27 Sep 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) systems.

25 Sep 2024

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

The Henry Royce Institute has published the Materials for Bioelectronics in Healthcare Strategy and Action Plan a comprehensive report that aims to help future-proof the UK’s bioelectronics for healthcare sector through materials innovation.

24 Sep 2024

Simple intervention can prevent lifelong disability in premature babies

Giving women at risk of premature birth a simple magnesium sulphate infusion (or 'drip') can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

24 Sep 2024

New two-dose HIV vaccine strategy shows promise for stronger immune response

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, allowing it to evade the antibody response generated by vaccines.

20 Sep 2024

Philanthropic investment establishes research center to advance precision diagnosis for diseases

An outstanding $21 million philanthropic investment will establish a pioneering research center to advance precision diagnosis for diseases that affect millions of Australians.

19 Sep 2024

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Rice University and Baylor College of Medicine have received $2.8 million in funding from the National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), for research on reducing inflammation and lung damage in acute respiratory distress syndrome (ARDS) patients.

19 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

Newcells Biotech launches high-content and high-throughput imaging suite to advance pre-clinical drug development programmes

Newcells Biotech (“Newcells”), a leading drug discovery partner specialising in the development of in vitro models and bespoke assay services to improve the prediction of in vivo human outcomes, today announced the launch of its imaging suite and advanced lung Fibroblast-to-Myofibroblast Transition (FMT) assay.

From Newcells Biotech 17 Sep 2024

Unveiling the mechanism behind DNA organization in early embryos

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos.

16 Sep 2024

Understanding the social determinants of cardiovascular health in Asian Americans

Numerous social and structural factors, including immigration status, socioeconomic position and access to health care, contribute to differences in cardiovascular health and heart disease risk for Asian Americans, and these factors affect Asian ethnic subgroups in different ways, according to a new scientific statement published today in the American Heart Association's journal, Circulation.

16 Sep 2024

Current and emerging biomarkers in the management of inflammatory bowel disease

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal (GI) tract that significantly impacts the quality of life of patients.

12 Sep 2024

New tool ehrapy revolutionizes health data analysis

Led by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for the analysis of complex medical health data.

12 Sep 2024

QB3-led team awarded $12 million to explore autism origins with advanced models

A QB3-led team uniting researchers from the University of California campuses at Berkeley, San Francisco, and Santa Cruz was awarded a $12 million grant from the California Institute for Regenerative Medicine (CIRM) to investigate the origins of autism using sophisticated cellular models called "neural organoids."

12 Sep 2024

AI tool enhances cancer diagnosis by transforming standard tissue images

VirtualMultiplexer transforms histology images into detailed cancer markers, streamlining diagnostics and enhancing patient outcomes through AI innovation.

12 Sep 2024

Endurance exercise transforms fat tissue and boosts metabolic health in adults with obesity

Regular endurance exercise significantly remodels abdominal subcutaneous fat in adults with obesity, enhancing its metabolic function and contributing to better cardiometabolic health.

11 Sep 2024

Fibrous scars drive glioblastoma recurrence

A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, surgery, and immunotherapy.

11 Sep 2024

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

A recent study published in Nature Machine Intelligence introduces an advanced artificial intelligence (AI) model capable of creating virtual colorations of cancer tissue.

10 Sep 2024

Sally Ross Soter donates $15 million to advance women’s heart health

Cardiovascular disease is the leading cause of death for women, and gaps in care and access persist between women and men.

9 Sep 2024

Translation News and Research

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

Genetic factors that make the bacteria behind cholera so dangerous uncovered

CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

Simple intervention can prevent lifelong disability in premature babies

New two-dose HIV vaccine strategy shows promise for stronger immune response

Philanthropic investment establishes research center to advance precision diagnosis for diseases

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

New biomarkers offer hope for early detection and prevention of Alzheimer's

Newcells Biotech launches high-content and high-throughput imaging suite to advance pre-clinical drug development programmes

Unveiling the mechanism behind DNA organization in early embryos

Understanding the social determinants of cardiovascular health in Asian Americans

Current and emerging biomarkers in the management of inflammatory bowel disease

New tool ehrapy revolutionizes health data analysis

QB3-led team awarded $12 million to explore autism origins with advanced models

AI tool enhances cancer diagnosis by transforming standard tissue images

Endurance exercise transforms fat tissue and boosts metabolic health in adults with obesity

Fibrous scars drive glioblastoma recurrence

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

Sally Ross Soter donates $15 million to advance women’s heart health

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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