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Novel PET radiopharmaceutical shows promising results in first-in-humans study

The preliminary trial results of a novel radiopharmaceutical for PET imaging of inflammation developed at the University of Turku, Finland, have been published.

16 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.”

16 Apr 2021

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for Coronavirus.

16 Apr 2021

Recovered COVID-19 patients may need only a single vaccine dose, suggests study

People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose, according to new research from the Penn Institute of Immunology. The findings, published today in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response.

16 Apr 2021

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Osteoarthritis affects the joints, but according to researcher Michael Zuscik, PhD, it may start in the gut.

15 Apr 2021

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS).

15 Apr 2021

Researchers identify two distinct phenotypes of COVID-19-associated ARDS

Approximately one in four patients hospitalized for the acute respiratory distress syndrome (ARDS) associated with severe COVID-19 infections may have a distinct phenotype (disease presentation) or biochemical profile associated with organ dysfunction, blood-clotting abnormalities and greater risk of death than patients with other, seemingly similar forms of the disease, researchers at Massachusetts General Hospital have found.

15 Apr 2021

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

Maintenance of good oral health may help prevent heart infection caused by mouth bacteria

Maintenance of good oral health is more important than use of antibiotics in dental procedures for some heart patients to prevent a heart infection caused by bacteria around the teeth, according to a new American Heart Association scientific statement published today in the association's flagship journal, Circulation.

15 Apr 2021

Heart Research UK funds new project investigating the effects of COVID-19 on blood vessels and blood pressure

A project at the University of Glasgow that is aiming to better understand the effects that COVID-19 infection has on blood vessels and blood pressure has received a grant of £250,000 from national charity Heart Research UK.

15 Apr 2021

High antibody and inflammatory mediator levels may predict severe COVID-19

A new study reports on biomarkers could help predict the progression of the viral illness to dangerous levels early enough to enable timely intervention.

15 Apr 2021

Adults with periodontitis transmit bacteria that can later cause the disease in their children

Adults with periodontitis transmit bacteria that can cause the disease in future to their children, and the bacteria remain in the oral cavity even when the children undergo treatment of various kinds, reinforcing the need for preventive care in the first year of a baby's life.

15 Apr 2021

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease.

15 Apr 2021

Cocoa consumption improves health of obese mice with liver disease

Supplementation of cocoa powder in the diet of high-fat-fed mice with liver disease markedly reduced the severity of their condition, according to a new study by Penn State researchers, who suggest the results have implications for people.

15 Apr 2021

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.

15 Apr 2021

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences.

15 Apr 2021

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future?

15 Apr 2021

Experimental evidence that ADAM17 inhibition prevents severe COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus that is contagious in humans. It is the causal agent of the ongoing coronavirus 2019 (COVID-19) pandemic. This virus causes a mild to severe infection and has claimed over 2.95 million lives worldwide. SARS-CoV-2 is the successor to SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak.

13 Apr 2021

Mouse model closely replicates human NAFLD

Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant.

13 Apr 2021

Inflammation News and Research

Novel PET radiopharmaceutical shows promising results in first-in-humans study

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

Recovered COVID-19 patients may need only a single vaccine dose, suggests study

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers identify two distinct phenotypes of COVID-19-associated ARDS

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Maintenance of good oral health may help prevent heart infection caused by mouth bacteria

Heart Research UK funds new project investigating the effects of COVID-19 on blood vessels and blood pressure

High antibody and inflammatory mediator levels may predict severe COVID-19

Adults with periodontitis transmit bacteria that can later cause the disease in their children

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

Cocoa consumption improves health of obese mice with liver disease

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Experimental evidence that ADAM17 inhibition prevents severe COVID-19

Mouse model closely replicates human NAFLD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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