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KAUST researchers refute challenges to targeted cancer therapy

Drugs that inhibit a key protein should offer new targeted cancer therapy for leukemia and breast cancer.

24 Aug 2023

Lung cells can be trained to counteract inflammation

Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 have been due to excessive inflammation, which results in acute lung injury.

24 Aug 2023

Researchers find link between topography of the genome and presence of cancer mutations

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

24 Aug 2023

The role played by the gut microbiome in metabolizing selected sweeteners

The current evidence on the role of the gut microbiome in metabolizing sweeteners and their metabolites.

24 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

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24 Aug 2023

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Researchers engineered and characterized a blood-brain barrier transport vehicle targeting the CD98 heavy chain of heterodimeric amino acid transporters.

24 Aug 2023

Study finds examining retinal structure could provide markers for Parkinson disease

A new paper examined the retinal data from Parkinson disease patients in attempt to identify disease markers.

24 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans -- an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

23 Aug 2023

UC researchers study parasite that causes Chagas disease

Almost everything about insects called kissing bugs is revolting, from the insidious way they bite people's faces at night to drink their blood while they sleep to the way they spread disease through their poop.

23 Aug 2023

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown.

23 Aug 2023

Griffith on the brink of technological breakthrough in vaccine development

Griffith University researchers are on the brink of a technological breakthrough in vaccine development with a possible new vaccine modality.

23 Aug 2023

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons.

23 Aug 2023

Skin signals neurons to grow the appropriate endings

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.

23 Aug 2023

New kidney tissue model could help assess safety of immunotherapy drugs

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.

23 Aug 2023

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.

23 Aug 2023

Study unveils how Cutibacterium acnes boosts epidermal lipids for enhanced barrier protection

The role of Cutibacterium acnes in improving the skin's barrier function.

23 Aug 2023

Study explores the role of N6-methyladensoine methylation and COVID-19

A recent study summarized the recent advances in the role of N6-methyladenosine (m6A) methylation in COVID-19.

23 Aug 2023

B Cell News and Research

KAUST researchers refute challenges to targeted cancer therapy

Lung cells can be trained to counteract inflammation

Researchers find link between topography of the genome and presence of cancer mutations

The role played by the gut microbiome in metabolizing selected sweeteners

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Study finds examining retinal structure could provide markers for Parkinson disease

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

UC researchers study parasite that causes Chagas disease

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Griffith on the brink of technological breakthrough in vaccine development

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

Skin signals neurons to grow the appropriate endings

New kidney tissue model could help assess safety of immunotherapy drugs

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Study unveils how Cutibacterium acnes boosts epidermal lipids for enhanced barrier protection

Study explores the role of N6-methyladensoine methylation and COVID-19

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