Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New form of idiopathic pulmonary fibrosis found

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disorder from which most patients die within 5 years after diagnosis.

30 May 2007

Largest ever Affymetrix GeneChip Microarray study

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has announced that it has completed the largest ever Affymetrix GeneChip Microarray study for a plant experimental system in an academic research setting.

28 May 2007

Genetic data overturns long-held theory of limb development

Long before animals with limbs (tetrapods) came onto the scene about 365 million years ago, fish already possessed the genes associated with helping to grow hands and feet (autopods) report University of Chicago researchers in Nature.

24 May 2007

Diets high in salt may increase stomach ulcers

Scientists from the Uniformed Services University of the Health Sciences (USU) have discovered that diets high in salt may increase the virulence of the pathogen Helicobacter pylori (H. pylori), which is the most common cause of ulcers in the stomach and duodenum.

24 May 2007

High salt intake increases gene activity in the ulcer-causing bacterium Helicobacter pylori

Scientists have identified yet another risk from a high-salt diet. High concentrations of salt in the stomach appear to induce gene activity in the ulcer-causing bacterium Helicobacter pylori, making it more virulent and increasing the likelihood of an infected person developing a severe gastric disease.

24 May 2007

Exercise rejuvenates muscle tissue in healthy senior citizens

Not only does exercise make most people feel better and perform physical tasks better, it now appears that exercise, specifically, resistance training -- actually rejuvenates muscle tissue in healthy senior citizens.

24 May 2007

Peering into the body and visualizing its molecular secrets one step closer to reality

Peering into the body and visualizing its molecular secrets, once the stuff of science fiction, is one step closer to reality with a study from researchers at the Stanford University School of Medicine and the University of California, San Diego School of Medicine.

22 May 2007

MIT researchers uncover surprising difference in gene regulation in mouse and human liver cells

Scientists often study mice as a model for human biology and disease, because their basic biological processes are assumed to be essentially the same as those of humans.

22 May 2007

In some species estrogen plays a key role in aggressiveness

Imagine if a naturally occurring chemical in your body could help make you feel more calm and relaxed ? but it would only work during the long days of summer.

22 May 2007

Decoding gene expression in cancer tumors using noninvasive imaging

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

22 May 2007

Link between extreme sleep disorder and onset of parkinsonism or dementia

Mayo Clinic researchers and a group of international collaborators have discovered a correlation between an extreme form of sleep disorder and eventual onset of parkinsonism or dementia.

17 May 2007

Important new gene-silencing mechanism

Genes provide the instructions used by the individual cells to produce the many different proteins that make up the body.

17 May 2007

Gene p53 thought to assist chemotherapy may help cancer thrive

A gene thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive.

16 May 2007

New understanding of ubiquitylation

It turns out there's more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought.

10 May 2007

New vitamin extends lifespan in yeast cells

Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer.

4 May 2007

RNA analysis can identify rejection in lung transplant patients

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

1 May 2007

Scientists discover pathway that promotes muscle cell survival in mice

Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell's ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles.

30 Apr 2007

Green tea may help prevent bone destruction in arthritis

In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.

30 Apr 2007

Exercise pill switches on master regulator that controls the ability of cells to burn fat

By giving ordinary adult mice a drug - a synthetic designed to mimic fat - Salk Institute scientist Dr. Ronald M. Evans is now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat.

30 Apr 2007

Environment rich in sensory stimuli restores memory in mice with neurodegeneration

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers.

30 Apr 2007