Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Study finds longer course of tamoxifen treatment cuts breast cancer deaths

The finding that women should be taking the drug for twice as long as is now customary came out of study of nearly 7,000 women from 36 countries.

7 Dec 2012

Positive results from NanoString's second clinical study of PAM50-based breast cancer assay

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostic products, today announced positive results from the second clinical validation study of its in vitro diagnostic breast cancer assay based on the PAM50 gene expression signature.

From NanoString Technologies 7 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Bio-Path Holdings, Inc., a biotechnology company developing a liposomal delivery technology for nucleic acid cancer drugs, today announced it is initiating development of its lead cancer drug BP-100-1.01 (Liposomal Grb-2) to treat triple negative breast cancer (TNBC) and inflammatory breast cancer (IBC), two cancers characterized by formation of aggressive tumors and relatively high mortality rates.

6 Dec 2012

Researchers examine impact of exercise on mare reproductive health and embryo transfer

In the latest issue of the Journal of Animal Science, researchers at Clemson University and the University of Florida examine the impact of exercise on mare reproductive health and embryo transfer.

6 Dec 2012

BMI influences hormone levels in overweight, obesity

A high body mass index has no significant impact on parameters of sperm quality, although it does lower serum levels of testosterone, luteinizing hormone, and prolactin, say researchers.

5 Dec 2012

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

AstraZeneca today announced the presentation of important new data from studies of FASLODEX (fulvestrant) Injection at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium taking place from 4-8 December at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

5 Dec 2012

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Selective targeting of the neurotransmitter that differentially affects brain cells that control the two distinct functions of the pancreas may allow for new medication therapies for conditions like diabetes, dyspepsia and gastro-esophageal reflux, according to Penn State College of Medicine researchers.

5 Dec 2012

Researchers investigate GPER receptor as possible new drug target for breast cancer

Five-year breast cancer survival rates have improved dramatically over the past 50 years, but tumors can recur up to ten or more years after they are detected. When tumors recur, they are even more difficult to treat.

5 Dec 2012

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

NOXXON Pharma today announced the treatment of the first patients in a Phase IIa clinical trial of its anti-hepcidin Spiegelmer NOX-H94 to treat anemia associated with chronic disease.

5 Dec 2012

Cabozantinib effectively treats prostate cancer spread to bones

A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.

5 Dec 2012

Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms

A pilot study to determine the best hormonal treatment for infantile spasms (IS) that may lead to changes in prescribing practices for hormone therapy is being presented for the first time at the American Epilepsy Society's 66th Annual Meeting in San Diego California.

4 Dec 2012

Researchers identify 4 new genetic regions that influence birth weight

Researchers have identified four new genetic regions that influence birth weight, providing further evidence that genes as well as maternal nutrition are important for growth in the womb. Three of the regions are also linked to adult metabolism, helping to explain why smaller babies have higher rates of chronic diseases later in life.

4 Dec 2012

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative.

3 Dec 2012

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

Childhood trauma can leave permanent epigenetic marks on DNA

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma.

3 Dec 2012

Orthopedic surgery relieves breast cancer metastases

Results of a review demonstrate the key role orthopedic surgery can play in the care of breast cancer patients with bone metastases.

30 Nov 2012

Study points to complexity of relationship between sleep duration and energy balance regulation

A new study suggests that increasing the amount of sleep that adults get could lead to reduced food intake, but the hormonal process differs between men and women.

30 Nov 2012

Needless fears linked to severity of autism symptoms in children

Most people know when to be afraid and when it's ok to calm down. But new research on autism shows that children with the diagnosis struggle to let go of old, outdated fears. Even more significantly, the Brigham Young University study found that this rigid fearfulness is linked to the severity of classic symptoms of autism, such as repeated movements and resistance to change.

30 Nov 2012

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Novartis will highlight more than 140 presentations on key data from its extensive oncology portfolio at the leading year-end scientific meetings devoted to hematology and breast cancer, demonstrating continued innovation in research and development efforts to advance the care of patients with cancer and rare diseases.

30 Nov 2012

Hormone News and Research

Further Reading

Study finds longer course of tamoxifen treatment cuts breast cancer deaths

Positive results from NanoString's second clinical study of PAM50-based breast cancer assay

Scientists identify key molecular pathway that leads to depression

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Researchers examine impact of exercise on mare reproductive health and embryo transfer

BMI influences hormone levels in overweight, obesity

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Researchers investigate GPER receptor as possible new drug target for breast cancer

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

Cabozantinib effectively treats prostate cancer spread to bones

Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms

Researchers identify 4 new genetic regions that influence birth weight

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Diabetes tests: an interview with Dr. Danielle Stowasser

Childhood trauma can leave permanent epigenetic marks on DNA

Orthopedic surgery relieves breast cancer metastases

Study points to complexity of relationship between sleep duration and energy balance regulation

Needless fears linked to severity of autism symptoms in children

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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