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Compounds extracted from parsley and dill seeds may help fight cancer

A team of Russian scientists from Moscow Institute of Physics and Technology, the N. D. Zelinsky Institute of Organic Chemistry, the Institute of Developmental Biology, and the Institute of Cell Biophysics proposed an efficient approach to a novel agents with anticancer activity.

29 Jun 2016

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies.

29 Jun 2016

Combined therapy approach could prove promising to treat brain cancer

A "combined therapy" approach to treating the most common form of brain cancer could prove promising, scientists say.

28 Jun 2016

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) — masses of immune cells— are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs.

28 Jun 2016

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's disease: that blocking an enzyme called c-Abl prevents the disease in specially bred mice, and that a chemical tag on a second protein may signal the disorder's presence and progression.

28 Jun 2016

Jefferson researchers discover alternate pathway that helps heart keep pumping

About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention.

28 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.

24 Jun 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle.

24 Jun 2016

Scientists provide new insights into role of star-shaped brain cells in memory, learning

A molecule that enables strong communication between our brain and muscles appears to also aid essential communication between our neurons, scientists report.

23 Jun 2016

New optical detection technology could be effective to monitor blood-glucose levels

A newly developed method for detecting glucose based on how it absorbs a specific type of light could spell the end of the painful, invasive finger-prick tests diabetics rely on to monitor their condition, says a Texas A&M University biomedical engineer who is developing the technology.

23 Jun 2016

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

MAIT cells of immune system can fight all sorts of bacterial and viral infections

Oxford University research has found that a little-studied and relatively unknown part of the human immune system could be twice as important as previously thought.

23 Jun 2016

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

One of the alterations that most affects the quality of life of the elderly is muscle wastage and the resulting loss of strength, a condition known as sarcopenia. At about 55 years old, people begin to lose muscle mass, this loss continues into old age, at which point it becomes critical.

22 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

Low mammographic breast density linked to worse prognosis in breast cancer patients

Even though dense breast tissue is a risk factor for breast cancer, very low mammographic breast density is associated with a worse prognosis in breast cancer patients.

21 Jun 2016

Highly efficient bacterial agent could improve treatment of Wilson disease

In the 'Journal of Clinical Investigation', scientists at the Helmholtz Zentrum München describe a small peptide that very efficiently binds excess copper from liver cells. This molecule comes from a bacterium's bag of tricks and could be suitable for treating Wilson disease.

21 Jun 2016

Researchers identify new myosin kinase that could optimize heart contractions

The heart is the only muscle that contracts and relaxes continuously over a lifetime to pump oxygen-rich blood to the body's organs. Researchers at UT Southwestern Medical Center now have identified a previously unrecognized enzyme that could optimize contraction and lead to new strategies to treat heart failure.

21 Jun 2016

Molecule News and Research

Compounds extracted from parsley and dill seeds may help fight cancer

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Combined therapy approach could prove promising to treat brain cancer

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Jefferson researchers discover alternate pathway that helps heart keep pumping

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Mutant fruit flies provide insight into origins of Parkinson's disease

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Scientists provide new insights into role of star-shaped brain cells in memory, learning

New optical detection technology could be effective to monitor blood-glucose levels

Scientists streamline total synthesis of uncialamycin drug

MAIT cells of immune system can fight all sorts of bacterial and viral infections

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

Researchers seek to develop novel antibody to treat glioblastoma

Low mammographic breast density linked to worse prognosis in breast cancer patients

Highly efficient bacterial agent could improve treatment of Wilson disease

Researchers identify new myosin kinase that could optimize heart contractions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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