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Scientists identify on/off obesity-induced switch to slow cancer progression

Having established that excessive fat tissue can fuel the growth of certain cancers, researchers have turned their attention to the molecular mechanisms involved in the process in the hopes of developing new cancer treatments.

21 Jun 2016

Rice University researchers synthesize new anti-cancer agent

Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand.

20 Jun 2016

New method helps analyse how cold viruses penetrate into cells

Cold viruses cause us irritation by penetrating into our cells and transporting their RNA into the cytoplasma of the infected cells. This is the only way they can multiply. The details of how the transfer of the RNA from within the virus occurs are difficult to study.

20 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

Natural molecule NAC could benefit patients with Parkinson's disease

The natural molecule, n-acetylcysteine (NAC), with strong antioxidant effects, shows potential benefit as part of the management for patients with Parkinson's disease, according to a study published today in the journal PLOS ONE.

17 Jun 2016

New molecular breast imaging gives better image quality with reduced radiation dose

Preliminary tests have demonstrated that a new device may enable existing breast cancer imagers to provide up to six times better contrast of tumors in the breast, while maintaining the same or better image quality and halving the radiation dose to patients.

17 Jun 2016

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis.

16 Jun 2016

New device may enable painless, effective diagnosis of Helicobacter in exhaled air

In the future, several illnesses can be quickly and painlessly diagnosed by the optical analysis of isotopes contained in exhaled air. VTT developed its first prototype for this purpose.

16 Jun 2016

New research paves way for potential notch-based anticancer therapeutics

A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines.

16 Jun 2016

TSRI scientists develop novel technique for finding drug candidates

Scientists at The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins.

16 Jun 2016

Already-approved drugs can fight apoptosis evasion in cancer

Cancer cells don't die when they're supposed to. Animal and human bodies follow an orderly process of birthing new cells and killing old ones. But cancer cells escape programmed cell death, called apoptosis, and multiply uncontrollably.

15 Jun 2016

New and inexpensive technique could help meet global demands for malaria drug

A new and inexpensive technique for mass-producing the main ingredient in the most effective treatment for malaria, artemisinin, could help meet global demands for the drug, according to a study to be published in the journal eLife.

15 Jun 2016

NCMC develops national roadmap for large-scale manufacturing of cell-based therapeutics

An industry-driven consortium has developed a national roadmap designed to chart the path to large-scale manufacturing of cell-based therapeutics for use in a broad range of illnesses including cancer, neuro-degenerative diseases, blood and vision disorders and organ regeneration and repair.

15 Jun 2016

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma.

15 Jun 2016

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

A paper by Brazilian researchers published in the journal Scientific Reports describes a study showing that a subgroup of olfactory neurons in the nasal cavity express a cellular receptor specializing in the transport of lipid molecules.

14 Jun 2016

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.

14 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

Amino acid acetylcarnitine may help predict neurobehavioral performance during chronic sleep loss

The amino acid acetylcarnitine may help predict an individual's neurobehavioral performance during chronic sleep restriction, according to results of a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania that will be presented at SLEEP 2016, the 30th annual meeting of the Associated Professional Sleep Societies LLC.

13 Jun 2016

New research offers more insights into development of Kennedy's disease

Kennedy's disease leads to progressive muscle wastage. It is a condition that affects only men and it appears between 40 and 50 years of age. There is no specific treatment available.

13 Jun 2016

Molecule News and Research

Scientists identify on/off obesity-induced switch to slow cancer progression

Rice University researchers synthesize new anti-cancer agent

New method helps analyse how cold viruses penetrate into cells

Scientists study fundamentals of tumour surveillance by immune system in mice models

Natural molecule NAC could benefit patients with Parkinson's disease

New molecular breast imaging gives better image quality with reduced radiation dose

S1P1R variation may cause differential patient responses to fingolimod treatment

New device may enable painless, effective diagnosis of Helicobacter in exhaled air

New research paves way for potential notch-based anticancer therapeutics

TSRI scientists develop novel technique for finding drug candidates

Already-approved drugs can fight apoptosis evasion in cancer

New and inexpensive technique could help meet global demands for malaria drug

NCMC develops national roadmap for large-scale manufacturing of cell-based therapeutics

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

T memory cells with naive phenotype can help boost immunity in older adults

Study shows similarity between embryonic and reprogrammed stem cells

Amino acid acetylcarnitine may help predict neurobehavioral performance during chronic sleep loss

New research offers more insights into development of Kennedy's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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