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Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

A team led by scientists at The Scripps Research Institute (TSRI) has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin.

1 Oct 2013

Virginia Tech faculty receives NIH New Innovator Award to research on influenza transmission

Influenza strikes five to 15 percent of the population and is estimated to cost the U.S. economy a hefty $90 million per year. If researchers can improve the understanding of how environmental conditions affect the ability of the influenza virus to survive and infect others while it is airborne, they may be able to help improve prediction and control of its spread.

1 Oct 2013

Vitamin D levels linked to emphysema

Researchers have found a relationship between emphysema and serum vitamin D levels, suggesting that the vitamin may play a role in modulating lung structure.

30 Sep 2013

Pfizer Licenses Gliknik's Pooled IVIG In $25M+ Deal

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30 Sep 2013

Researchers discover how aspirin improves survival in patients with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress heard today (Monday).

30 Sep 2013

Men with prostate cancer experience more harm than good from routine PSA screening

Prostate cancer screening using the prostate-specific antigen test is widely used in France despite a lack of evidence showing that it reduces cancer deaths. Now, researchers have shown that men experience more harm than good from routine PSA screening, according to research to be presented today (Monday) by Professor Mathieu Boniol, at the 2013 European Cancer Congress.

30 Sep 2013

Biology of tumour more important than primary site, say researchers

Identifying the molecular profile of a tumour where the primary site is unknown is crucial to the choice of treatment, the 2013 European Cancer Congress, will hear on Monday.

30 Sep 2013

Scientists discover two new compounds that could help treat CF patients having common mutation

Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes), led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation.

30 Sep 2013

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

New results from a trial of an antibody that helps the immune system to recognise and attack cancer cells have shown particularly encouraging responses in patients who are smokers or former smokers.

30 Sep 2013

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

The first Phase II study to investigate the use of the anti-cancer drug, everolimus, for the initial treatment of advanced papillary kidney cancer has shown that it is successful in slowing or preventing the spread of the disease, according to research to be presented today (Sunday) at the 2013 European Cancer Congress.

29 Sep 2013

Scientists unravel secrets of mechanism that snips our genes

Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.

27 Sep 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

A little-used class of antidepressants appears potentially effective in combating a particularly deadly form of lung cancer, according to a new study from researchers at the Stanford University School of Medicine.

27 Sep 2013

Study shows how maternal viral infection may increase risk of having child with autism

Activating a mother's immune system during her pregnancy disrupts the development of neural cells in the brain of her offspring and damages the cells' ability to transmit signals and communicate with one another, researchers with the UC Davis Center for Neuroscience and Department of Neurology have found.

27 Sep 2013

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

The mood changes of a 'Jekyll-and-Hyde' protein, which sometimes boosts tumour cell growth and at other times suppresses it, have been explained in a new study led by Oxford University researchers.

27 Sep 2013

New ultra-specific test now available for prostate cancer

A new urine test for prostate cancer that measures minute fragments of RNA is now commercially available to men nationwide through the University of Michigan MLabs.

27 Sep 2013

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

The Center of Reproductive Medicine today announced its participation in the Thrive-IVF Research Study, a Phase 2 clinical trial sponsored by Nora Therapeutics, Inc., to evaluate the efficacy, safety and tolerability of NT100 in women who have had repeated in vitro fertilization (IVF) failures despite having good quality embryos.

26 Sep 2013

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today entered into an agreement with Active Motif, a leading provider of kits and reagents to enable epigenetics research.

26 Sep 2013

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Three grants totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice. The awards are from the National Institutes of Health.

26 Sep 2013

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish a front line of defense at mucosal surfaces.

26 Sep 2013

G Protein News and Research

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

Virginia Tech faculty receives NIH New Innovator Award to research on influenza transmission

Vitamin D levels linked to emphysema

Pfizer Licenses Gliknik's Pooled IVIG In $25M+ Deal

Researchers discover how aspirin improves survival in patients with colon cancer

Men with prostate cancer experience more harm than good from routine PSA screening

Biology of tumour more important than primary site, say researchers

Scientists discover two new compounds that could help treat CF patients having common mutation

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

Scientists unravel secrets of mechanism that snips our genes

Study indicates that RNA translation is dictated by translational hotspots

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

Study shows how maternal viral infection may increase risk of having child with autism

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

New ultra-specific test now available for prostate cancer

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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