Inflammation News and Research

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Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Through an analysis of cellular components (cell fractions) from malignant ascites (fluid buildup in the abdomen caused by gastric cancer), a research collaboration based in Kumamoto University (Japan) has demonstrated that cellular senescence of cancer-associated fibroblasts (CAFs) play an important role in the peritoneal dissemination of gastric cancer foci (cells different from surrounding cells).

23 Mar 2021

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

Serious complications due to blood clots, such as heart attacks and strokes, that are experienced by some COVID-19 survivors may be caused by a lingering immune response in the blood vessels after recovery, suggests a study published today in eLife.

23 Mar 2021

Stem cell therapy could help restore debilitating age-related muscle loss

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

23 Mar 2021

Vigorous physical activity can curb adiposity-induced low-grade inflammation in children

According to a recent Finnish study, accumulating more brisk and vigorous physical activity can curb adiposity-induced low-grade inflammation.

23 Mar 2021

Biological “feed-forward” loop contributes to progression of osteoarthritis

An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis.

23 Mar 2021

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine.

23 Mar 2021

Biological feed-forward loop drives cartilage cells in an arthritic joint to contribute to progression of the disease

23 Mar 2021

Study may help develop effective biosensors for non-invasive diagnosis of prostate cancer

The efficacy of biosensors used in clinical tests depends critically on the surface of the device on which the biorecognition molecules are immobilized.

23 Mar 2021

Study identifies metabolic processes associated with multiple, unrelated diseases

Many older, but also increasingly younger, people suffer from several diseases at the same time. Scientists at the Berlin Institute of Health at Charité – Universitätsmedizin Berlin, together with colleagues from Munich and the United Kingdom, have now identified common risk factors that predispose to multiple even seemingly unrelated diseases.

22 Mar 2021

Disease-driving B cells play a role in the development of NAFLD

New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) - the most common chronic liver condition in the U.S.

22 Mar 2021

RedHill provides opaganib treatment under compassionate use exemption for Swiss COVID-19 patients

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that it has acted on a request to provide opaganib treatment on an outpatient basis under compassionate use exemption for several Swiss patients suffering from COVID-19 pneumonia.

22 Mar 2021

Sealing fistulas more effectively with water-immiscible mussel protein-based bioadhesive

A Korean research team has recently developed an innovative vesico-vaginal fistula treatment method using the mussel adhesive protein (MAP) that can effectively seal fistulas in organs even when exposed to urine.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

"The AMNOG procedure has passed its first practical test. It is practicable and can also be implemented in detail", emphasized IQWiG's Director Jürgen Windeler in October 2011, when the Institute had published its first early benefit assessment within the framework of the AM-NOG procedure (AMNOG = Act on the Reform of the Market for Medicinal Products).

22 Mar 2021

Researchers develop tools to detect chemical signals between the brain and immune system

If it seems like your stomach has a mind of its own, you're not wrong. University of Cincinnati assistant professor Ashley Ross says your body is full of neurons that regulate digestion, inflammation and a host of other biological processes.

22 Mar 2021

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 kB viral genomes and subgenomic viral RNAs. However, how this is achieved is largely unknown.

21 Mar 2021

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

A new peer-reviewed study published in the journal Toxicological Research & Application shows acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression compared to smoke from combustible cigarettes.

21 Mar 2021

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in chronic inflammation and cancer.

20 Mar 2021

Study reveals worsening health profiles in Gen X and Gen Y

Recent generations show a worrying decline in health compared to their parents and grandparents when they were the same age, a new national study reveals.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Inflammation News and Research

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

Stem cell therapy could help restore debilitating age-related muscle loss

Vigorous physical activity can curb adiposity-induced low-grade inflammation in children

Biological “feed-forward” loop contributes to progression of osteoarthritis

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Biological feed-forward loop drives cartilage cells in an arthritic joint to contribute to progression of the disease

Study may help develop effective biosensors for non-invasive diagnosis of prostate cancer

Study identifies metabolic processes associated with multiple, unrelated diseases

Disease-driving B cells play a role in the development of NAFLD

RedHill provides opaganib treatment under compassionate use exemption for Swiss COVID-19 patients

Sealing fistulas more effectively with water-immiscible mussel protein-based bioadhesive

Male fertility and androgen production may be impacted by COVID-19

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

Researchers develop tools to detect chemical signals between the brain and immune system

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Study reveals worsening health profiles in Gen X and Gen Y

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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