Clinical Trial News and Research

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Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Data-driven tool defines risk stages for children with chronic kidney disease

Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children.

10 Apr 2018

Japanese researchers develop new compound to enhance recovery of stroke patients

A team of Japanese researchers have developed a new compound that enhanced motor function recovery after brain damage in animal tests, according to a study published in the journal Science.

10 Apr 2018

New system promises greater accuracy in determining heart transplant rejection and injury

The results of an international clinical trial for a new system of diagnosing heart transplant rejection and injury will be presented publicly for the first time at the International Society for Heart & Lung Transplantation annual meeting, which will take place on April 11 and 12 in Nice, France.

10 Apr 2018

Houston Methodist-led research focuses on rare, inherited neurodegenerative disorder

A rare, inherited neurodegenerative disorder will soon be the focus of an international clinical research effort led by Houston Methodist and funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

10 Apr 2018

New class of drug holds potential to help patients with treatment-resistant cancers

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.

10 Apr 2018

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

First-in-human clinical trial of retinal implant to treat dry AMD

Age-related macular degeneration (AMD) affects more than 1.75 million individuals in the United States. Because the population is aging, that number will increase to almost 3 million by 2020. Between 80 and 90 percent of cases in this country are the dry version of the condition, for which no effective treatment exists.

5 Apr 2018

App-based self-acupressure benefits women with menstrual pain

Can acupressure achieve a sustained reduction in menstrual pain? Is an app-based self-care program particularly attractive to young women? These questions addressed in a new study by researchers from Charité - Universitätsmedizin Berlin, the results of which have been published in the American Journal of Obstetrics and Gynecology.

4 Apr 2018

Older Americans are hooked on vitamins despite scarce evidence they work

When she was a young physician, Dr. Martha Gulati noticed that many of her mentors were prescribing vitamin E and folic acid to patients. Preliminary studies in the early 1990s had linked both supplements to a lower risk of heart disease.

4 Apr 2018

UC San Diego Health designated as LBDA Research Center of Excellence

The Lewy Body Dementia Association, announced today that UC San Diego Health has been named a LBDA Research Centers of Excellence, a partnership of 24 pre-eminent academic medical research centers across the United States. LBDA is a leading advocacy group dedicated to raising awareness and advancing research and treatment of Lewy body dementia.

3 Apr 2018

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus

3 Apr 2018

Hypertension before pregnancy can raise risk of miscarriage

A new study has found that young women who have high blood pressure before their pregnancy are at a greater risk of suffering from a miscarriage. This is true for women who have not been diagnosed with hypertension but have an elevated blood pressure. The study was conducted at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and is due to appear in the May 2018 issue of the journal Hypertension.

2 Apr 2018

Higher protein intake may not benefit older adults

Regardless of whether an adult is young or old, male or female, their recommended dietary allowance for protein, set by the Institute of Medicine, is the same: 0.8-g/kg/day. Many experts and national organizations recommend dietary protein intakes greater than the recommended allowance to maintain and promote muscle growth in older adults.

2 Apr 2018

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).

30 Mar 2018

Wound protector use linked to statistically significant reduction in SSI, study shows

Surgical site infection is a common occurrence among patients who have had gastrointestinal surgery, with reported infection rates varying from 4 to 25 percent.

30 Mar 2018

First-of-its-kind cancer drug effective in 93% of pediatric patients

A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern's Simmons Cancer Center announced.

30 Mar 2018

Leukemia itself may increase risk for long-term neurocognitive problems in survivors

Leukemia itself, not just side effects related to its treatment, may increase the risk for long-term problems with attention, organization and related neurocognitive skills in survivors of the most common childhood cancer, according to research from St. Jude Children's Research Hospital. The study appears today in the journal JAMA Oncology.

29 Mar 2018

Natural dietary supplement tends to improve blood pressure and arterial health

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

29 Mar 2018

Clinical Trial News and Research

Biomarker panel can guide future therapeutic decisions for glioma patients

Data-driven tool defines risk stages for children with chronic kidney disease

Japanese researchers develop new compound to enhance recovery of stroke patients

New system promises greater accuracy in determining heart transplant rejection and injury

Houston Methodist-led research focuses on rare, inherited neurodegenerative disorder

New class of drug holds potential to help patients with treatment-resistant cancers

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using Cord Blood to Alleviate the Symptoms of Autism

First-in-human clinical trial of retinal implant to treat dry AMD

App-based self-acupressure benefits women with menstrual pain

Older Americans are hooked on vitamins despite scarce evidence they work

UC San Diego Health designated as LBDA Research Center of Excellence

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Hypertension before pregnancy can raise risk of miscarriage

Higher protein intake may not benefit older adults

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

Wound protector use linked to statistically significant reduction in SSI, study shows

First-of-its-kind cancer drug effective in 93% of pediatric patients

Leukemia itself may increase risk for long-term neurocognitive problems in survivors

Natural dietary supplement tends to improve blood pressure and arterial health

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