Genes News and Research

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New testing technology can accurately differentiate between viral and bacterial infections

When patients complain of coughing, runny nose, sneezing and fever, doctors are often stumped because they have no fundamental tool to identify the source of the respiratory symptoms and guide appropriate treatments.

4 May 2021

Researchers develop new technology to reduce high error rates in gene sequencing

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

4 May 2021

New drug class effective in treating certain types of ovarian cancers

A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build up a resistance to chemotherapy.

4 May 2021

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Studying protein changes in the kidneys as we age, as well as the transcription of genes into proteins, helps provide a full picture of the age-related processes that take place in these organs, says a study in mice published today in eLife.

4 May 2021

What happens in the first few days of SARS-CoV-2 infection?

New research, published in PLOS Biology, has evaluated SARS-CoV-2 infection in primary cultures of well-differentiated cells to determine how the virus affects the body and how the infection starts. Answers to these questions are essential to forming a general understanding of viral pathogenesis, which helps us develop effective prevention and treatment strategies for COVID-19.

4 May 2021

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

4 May 2021

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

In a paper recently uploaded to the preprint server medRxiv by Edward Málaga Trillo et al. (April 29th, 2021), these methods are tested in combination with CRISPR-Cas detection in the field, demonstrating a sensitivity and specificity of 93.8% and 99%, respectively.

4 May 2021

Differential NK cell activity found to contribute to SARS-CoV-2 infection resistance

The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide and is the leading cause of mortality in Brazil in 2020 as well as early 2021. Clinical manifestations of COVID-19 disease range from no symptoms and mild flu-like symptoms to severe cases leading to hospitalization and death.

3 May 2021

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly.

3 May 2021

Scientists investigate the role played by genes and environment in multiple substance use

Many drug addicts take not only one substance but rather several. Scientists at the Max Planck Institute of Experimental Medicine in Göttingen have investigated the role that genes and the environment play in the development of such multiple substance consumption or polytoxicomania.

3 May 2021

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

An interesting new study discusses how adaptive cellular immunity against the SARS-CoV-2 is dependent on differences in HLA-encoding genes between patients.

3 May 2021

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Scientists from several hospitals and research centers have shown what happens in individual cells of patients who died of COVID-19. In a study published in Nature, the researchers describe how infected cells from multiple organs exhibited a range of molecular and genomic changes.

3 May 2021

Could CRISPR be used as a SARS-CoV-2 antiviral?

The potential of using this gene manipulation technology as a SARS-CoV-2 inhibitor or prophylactic is investigated in a review recently uploaded to the journal Experimental Biology and Medicine (April 25th, 2021) by Arnab Banerjee and colleagues.

2 May 2021

Live "attenuated" influenza virus vaccine protects animals against respiratory infections, including SARS-CoV-2

Researchers in the United States and Austria have demonstrated the potential of a modified influenza virus as a vaccine to protect against viral respiratory pathogens, including the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).

2 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

The National Institute of Environmental Health Sciences has awarded Byron C. Jones, PhD, professor in the Department of Genetics, Genomics, and Informatics at the University of Tennessee Health Science Center, $2.87 million for his continuing study of genetic alterations associated with Gulf War illness among former military personnel.

30 Apr 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

The National Cancer Institute (NCI), part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

29 Apr 2021

Is Hong Kong’s fourth wave of COVID-19 due to the Q57H SARS-CoV-2 variant?

A recent article in the Centers for Disease Control and Prevention (CDC)’s Emerging Infectious Diseases reveals that the last of these was probably due to the introduction of a new variant from Nepal. This novel variant had been circulating in the community for about a month before the last outbreak was reported.

29 Apr 2021

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

Genes News and Research

New testing technology can accurately differentiate between viral and bacterial infections

Researchers develop new technology to reduce high error rates in gene sequencing

New drug class effective in treating certain types of ovarian cancers

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

What happens in the first few days of SARS-CoV-2 infection?

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

Differential NK cell activity found to contribute to SARS-CoV-2 infection resistance

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Scientists investigate the role played by genes and environment in multiple substance use

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Could CRISPR be used as a SARS-CoV-2 antiviral?

Live "attenuated" influenza virus vaccine protects animals against respiratory infections, including SARS-CoV-2

Correcting mutations in muscle stem cells using new gene-editing technology

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

Is Hong Kong’s fourth wave of COVID-19 due to the Q57H SARS-CoV-2 variant?

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Cell biology (5th edition)

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