Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Lotus Pharmaceutical submits generic Xenical ANDA with FDA

Lotus Pharmaceutical Company Inc. has confirmed its submission of Abbreviated New Drug Application for Orlistat capsules, a generic version of Xenical, to the US Food and Drug Administration (FDA).

11 Dec 2012

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that is crucial to new drug development.

11 Dec 2012

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

The U.S. Food and Drug Administration today expanded the approved use of Zytiga (abiraterone acetate) to treat men with late-stage (metastatic) castration-resistant prostate cancer prior to receiving chemotherapy.

10 Dec 2012

Natural product to combat menopause symptoms

Menopause is a time of great changes for most women, but information about this change of life is often sparse and contradictory. Options for symptom relief are limited. Natural products can be a healthier alternative and can provide symptom relief

10 Dec 2012

New study could help develop anti-inflammatory drugs with fewer side effects

10 Dec 2012

Genzyme receives EC approval for Thyrogen product label expansion

Genzyme, a Sanofi company, today announced it has received European Commission approval of a product label expansion for the use of Thyrogen (thyrotropin alfa) with a wider irradiation dose range for postoperative thyroid remnant ablation.

10 Dec 2012

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

Research from The Cancer Institute of New Jersey shows that an ultra-shortened, accelerated breast irradiation treatment using a balloon device is both logistically achievable and tolerable. The work will be offered during a poster presentation at the 35th Annual CTRC-AACR San Antonio Breast Cancer Symposium this week. The Cancer Institute of New Jersey is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (RWJMS).

7 Dec 2012

VA to offer new rules for veterans with brain injuries

The new regulations will make it easier for veterans with traumatic brain injuries to get health care. And, an agreement between the VA and the Indian Health Service will allow some vets to get care closer to home.

7 Dec 2012

First Edition: December 7, 2012

Today's early morning highlights from the major news organizations includes articles on the talks between President Barack Obama and House Speaker John Boehner on the "fiscal cliff."

7 Dec 2012

Study finds longer course of tamoxifen treatment cuts breast cancer deaths

The finding that women should be taking the drug for twice as long as is now customary came out of study of nearly 7,000 women from 36 countries.

7 Dec 2012

Positive results from NanoString's second clinical study of PAM50-based breast cancer assay

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostic products, today announced positive results from the second clinical validation study of its in vitro diagnostic breast cancer assay based on the PAM50 gene expression signature.

From NanoString Technologies 7 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Bio-Path Holdings, Inc., a biotechnology company developing a liposomal delivery technology for nucleic acid cancer drugs, today announced it is initiating development of its lead cancer drug BP-100-1.01 (Liposomal Grb-2) to treat triple negative breast cancer (TNBC) and inflammatory breast cancer (IBC), two cancers characterized by formation of aggressive tumors and relatively high mortality rates.

6 Dec 2012

Researchers examine impact of exercise on mare reproductive health and embryo transfer

In the latest issue of the Journal of Animal Science, researchers at Clemson University and the University of Florida examine the impact of exercise on mare reproductive health and embryo transfer.

6 Dec 2012

BMI influences hormone levels in overweight, obesity

A high body mass index has no significant impact on parameters of sperm quality, although it does lower serum levels of testosterone, luteinizing hormone, and prolactin, say researchers.

5 Dec 2012

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

AstraZeneca today announced the presentation of important new data from studies of FASLODEX (fulvestrant) Injection at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium taking place from 4-8 December at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

5 Dec 2012

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Selective targeting of the neurotransmitter that differentially affects brain cells that control the two distinct functions of the pancreas may allow for new medication therapies for conditions like diabetes, dyspepsia and gastro-esophageal reflux, according to Penn State College of Medicine researchers.

5 Dec 2012

Hormone News and Research

Further Reading

Lotus Pharmaceutical submits generic Xenical ANDA with FDA

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

Natural product to combat menopause symptoms

New study could help develop anti-inflammatory drugs with fewer side effects

Genzyme receives EC approval for Thyrogen product label expansion

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

VA to offer new rules for veterans with brain injuries

First Edition: December 7, 2012

Study finds longer course of tamoxifen treatment cuts breast cancer deaths

Positive results from NanoString's second clinical study of PAM50-based breast cancer assay

Scientists identify key molecular pathway that leads to depression

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Researchers examine impact of exercise on mare reproductive health and embryo transfer

BMI influences hormone levels in overweight, obesity

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Researchers investigate GPER receptor as possible new drug target for breast cancer

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

Cabozantinib effectively treats prostate cancer spread to bones

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