Immune System News and Research

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BCG vaccine formulations vary widely in their characteristics, study shows

Each year, more than 100 million newborns around the world receive vaccinations against Mycobacterium tuberculosis, or TB, which infects about one-quarter of the world's population.

28 Jan 2020

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria.

28 Jan 2020

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Microbes are often seen as pathogens that cause disease, but the picture is actually more complex than that limited view.

28 Jan 2020

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children's) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic Granulomatosis (X-CGD), a rare and severe immune dysfunction. Six of them are free of treatment for complications generated by the disease.

28 Jan 2020

What parents need to know about the HPV vaccine

The vaccine that prevents infection from human papillomavirus (HPV) is nothing short of a medical marvel.

28 Jan 2020

An old plant virus inspires the design of novel second-generation malaria vaccine

Scientists from the Walter Reed Army Institute of Research have demonstrated that a novel, second-generation malaria vaccine candidate based on the tobacco mosaic virus may offer protection against Plasmodium falciparum malaria in the upcoming issue of the journal Proceedings of the National Academy of Sciences.

27 Jan 2020

Preterm survival rate up by 25 percent thanks to the quality improvement program

Preterm birth occurs before 37 weeks of gestation and has been tied to many complications in the infant. In Canada, the rate of survival of very preterm infants born between 28 to 32 weeks, improved by 25 percent, thanks to the national Evidence-based Practice for Improving Quality (EPIQ) program in neonatal intensive care units (NICUs) across the country.

27 Jan 2020

Discovery could unlock new ways to treat a rare blood disease

A cancer researcher at the University of Alberta has made a discovery that could unlock new ways to treat a rare blood disease.

27 Jan 2020

Keto diet produces health benefits in the short term, Yale study finds

A ketogenic diet -- which provides 99% of calories from fat and only 1% from carbohydrates -- produces health benefits in the short term, but negative effects after about a week, Yale researchers found in a study of mice.

27 Jan 2020

Taming pathogens with mucus and phages

Millions of people are treated with antibiotics each year for infections or as a preventative measure. The Centers for Disease Control and Prevention reports that at least 2.8 million people are infected with antibiotic-resistant bacteria each year, meaning the germs have found ways to overpower antibiotics and continue to grow.

24 Jan 2020

First glioblastoma patient treated with genetically modified poliovirus at UH

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma, a deadly Grade IV cancer of the brain.

24 Jan 2020

Coronavirus could turn into a new pandemic

With news that the coronavirus called 2019-nCoV is capable of spreading from human to human, many are concerned about the possibility of a new pandemic, and that is not outside the realm of possibility, according to Jeff Hogan, a professor and infectious disease expert at the University of Georgia, who studied the SARS coronavirus extensively.

24 Jan 2020

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Toxoplasma gondii is best known as the parasite that may lurk in a cat's litter box. Nearly a third of the world's population is believed to live with a chronic Toxoplasma infection.

24 Jan 2020

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract.

24 Jan 2020

New vaccine against African swine fever appears to be more effective than previous vaccines

Government and academic investigators have developed a vaccine against African swine fever that appears to be far more effective than previously developed vaccines. The research appears this week in the Journal of Virology, a publication of the American Society for Microbiology.

23 Jan 2020

Emerging public health concern about Wuhan coronavirus

Since December, a new coronavirus that originated in Wuhan, China, has killed at least 17 people and sickened close to 600. Cases continue to spread globally, with one identified in Washington state.

23 Jan 2020

Combination of two immune defense strategies could afford alternative approach to treating sepsis

The human immune system uses two pre-programmed strategies to tackle infection. One is fever, a resistance mechanism that tries to eliminate a pathogen by raising the body's temperature.

23 Jan 2020

Immune system cells facilitate the invasive capacity of glioblastoma

In a study published in Brain Communications, a new Open Access publication of the well-known journal Brain, the team led by Carlos Barcia, researcher at Institut de Neurociències of the Universitat Autònoma de Barcelona, analyzed the role of immune cells in the expansion of glioblastoma, the most aggressive brain tumor.

23 Jan 2020

New study gives hope for potentially developing a cure for HIV

HIV latency is considered one of the biggest challenges to developing a cure for the virus.

23 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Immune System News and Research

BCG vaccine formulations vary widely in their characteristics, study shows

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

What parents need to know about the HPV vaccine

An old plant virus inspires the design of novel second-generation malaria vaccine

Preterm survival rate up by 25 percent thanks to the quality improvement program

Discovery could unlock new ways to treat a rare blood disease

Keto diet produces health benefits in the short term, Yale study finds

Taming pathogens with mucus and phages

First glioblastoma patient treated with genetically modified poliovirus at UH

Coronavirus could turn into a new pandemic

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

New vaccine against African swine fever appears to be more effective than previous vaccines

Emerging public health concern about Wuhan coronavirus

Combination of two immune defense strategies could afford alternative approach to treating sepsis

Immune system cells facilitate the invasive capacity of glioblastoma

New study gives hope for potentially developing a cure for HIV

Scientists reverse HIV latency, take major scientific step toward curative therapies

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