Molecule News and Research

RSS

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Okayama University researchers report that the overexpression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal Diabetes, March 2016, may fuel the development of new therapies targeting these diseases.

9 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

We control their electrical activity. Cardiac cells are capable of producing and transmitting electric signals through changes in a cell membrane potential.

9 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

New antibody-based therapy may provide better strategy for long-term control of HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

9 May 2016

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and the Fred Hutchinson Cancer Research Center report today, May 5, in the journal Cell.

6 May 2016

T cell gives precise mechanical tugs to detect friends and foes

T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.

6 May 2016

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

A protein called Bim may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma, according to the results of a study by Mayo Clinic researchers led by senior author Haidong Dong, M.D., Ph.D., and published online in the May 5 edition of JCI Insight.

6 May 2016

CSL362 antibody targets, depletes pDCs and other cells implicated in SLE

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems. Autoantibodies, which are produced by B cells, contribute to development of SLE.

6 May 2016

MDI Biological Laboratory to offer one-week course in Quantitative Fluorescence Microscopy

Science professionals, doctoral and postdoctoral students from across the country will gather May 20 through 27 at the MDI Biological Laboratory in Bar Harbor, Maine, for an intensive one-week course in Quantitative Fluorescence Microscopy.

6 May 2016

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Loss of appetite during illness is a common and potentially debilitating phenomenon--in cancer patients, especially, it can even shorten lifespan.

5 May 2016

Blueberry component PS may protect against dry eye disease

Pterostilbene (PS), a component of blueberries, have been found to protect against dry eye disease according to a new study.

5 May 2016

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

Researchers develop molecule that binds to GAA enzymes key to progress of Pompe disease

Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.

4 May 2016

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

Aging takes its toll on the brain, and the cells of the hippocampus--a brain region with circuitry crucial to learning and memory--are particularly vulnerable to changes that can lead to Alzheimer's disease or cognitive decline. With the hope of counteracting the changes that can lead to these two conditions, researchers at Rockefeller University and their colleagues have begun examining the effects of a drug known to affect this circuitry.

4 May 2016

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

In a step forward in the push for targeted treatments that can block the specific molecular malfunctions driving cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation can drive the most common type of lymphoma as well as melanoma, the deadliest form of skin cancer.

3 May 2016

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms.

3 May 2016

Molecule News and Research

lncRNA in placenta may help protect unborn baby from invading pathogens

TSRI scientists design potential drug candidate to treat triple negative breast cancer

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Food deprivation may help treat fatty liver disease

Scientists develop new technology that helps visualize translation of mRNA into proteins

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

New antibody-based therapy may provide better strategy for long-term control of HIV

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

T cell gives precise mechanical tugs to detect friends and foes

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

CSL362 antibody targets, depletes pDCs and other cells implicated in SLE

MDI Biological Laboratory to offer one-week course in Quantitative Fluorescence Microscopy

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Blueberry component PS may protect against dry eye disease

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers develop molecule that binds to GAA enzymes key to progress of Pompe disease

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News