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Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer.

14 Jan 2020

Study shows how treatment resistance develops in patients with bile duct cancer

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows how resistance to a promising targeted drug develops in patients with a rare, lethal cancer of the bile ducts called cholangiocarcinoma.

14 Jan 2020

Skin-protecting antibody may promote tumor growth during chronic tissue inflammation

One of the skin's defenses against environmental assault can help tumors to grow when skin is exposed to chronic inflammation, finds a study in mice published today in eLife.

14 Jan 2020

Bath scientists identify promising route to develop new treatments for skin cancer

A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumor growth.

14 Jan 2020

Study shows how cancer-causing genes promote metastasis

Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing.

14 Jan 2020

Exosome treatment promotes remarkable stroke recovery in swine models

It's been almost a quarter century since the first drug was approved for stroke. But what's even more striking is that only a single drug remains approved today.

14 Jan 2020

NUS researchers discover new personalized tool for cancer diagnosis

A team of researchers from the National University of Singapore has discovered a new personalized tool to detect cancer, predict patient survivability and how well a cancer patient would respond to immunotherapy.

14 Jan 2020

NAU scientists in search of a powerful combination of melanoma-fighting drugs

Melanoma is the most lethal type of skin cancer and unusually common in Arizona, where residents are exposed to higher-than-average amounts of ultraviolet radiation.

13 Jan 2020

Updated breast cancer guideline offers recommendations for handling cases with low ER expression

The updated guideline for estrogen and progesterone receptor (ER/PgR) testing in breast cancer, published jointly today by the College of American Pathologists and the American Society of Clinical Oncology, reaffirms much of the original guidance and has more specific recommendations for handling and reporting cases with low ER expression.

13 Jan 2020

The circadian clock is key to reducing radiation‐induced cardiotoxicity

Treatment for breast cancer commonly includes radiation therapy, which offers good chances of success but comes with a serious long-term side effect: toxicity due to radiation that reaches the heart, causing DNA damage in healthy heart cells. Over time, this can lead to heart disease and eventually heart failure.

13 Jan 2020

Lymphopenia may hint a higher risk of future illness, death

Lymphopenia, which indicates lower levels of lymphocytes in the blood, has been tied to a higher risk of future illness and death, a new study found.

13 Jan 2020

Researchers identify how marijuana accelerates growth of HPV-related head and neck cancer

University of California San Diego School of Medicine researchers have identified the molecular mechanism activated by the presence of tetrahydrocannabinol (THC) - the ingredient that causes people to feel the euphoria or "high" associated with cannabis - in the bloodstream that accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck squamous cell carcinoma.

13 Jan 2020

The Riney Family Multiple Myeloma Initiative to be established at Dana-Farber

Dana-Farber Cancer Institute will establish the Riney Family Multiple Myeloma Initiative to help improve outcomes and accelerate understanding of the underlying biology for the most challenging types of myelomas, cancers that form in a type of white blood cell called a plasma cell.

13 Jan 2020

UniSA researcher receives grant to develop personalized cancer treatment

Personalized cancer treatment is one step closer to becoming a reality for more patients, thanks to a Cancer Council Beat Cancer Project grant awarded to the University of South Australia researcher Dr. Stephanie Reuter Lange to explore how computer-based modeling can optimize cancer treatment and remove the need for expensive clinical trials.

13 Jan 2020

New tool judges accuracy of computer predictions of tumor’s genetic diversity

Cancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly susceptible or resistant to a given treatment. As a result, identifying these variations can help clinicians decide which treatment is most likely to be successful for a specific patient.

10 Jan 2020

Researchers discover important role for macropinocytosis in mammalian cell growth

For the first time, researchers at Michigan Medicine have demonstrated that a cellular process known to be involved in cancer and other diseases also plays an important role in the growth of at least one type of normal mammalian cell.

10 Jan 2020

Flash Radiotherapy could Deliver all the Radiation Needed in One Rapid Treatment

Researchers at the University of Pennsylvania have demonstrated that a new approach to delivering radiation could one day mean that cancer patients will be able to receive their entire course of radiotherapy within less than a second as opposed to several weeks.

10 Jan 2020

New framework developed to estimate the growth of individual cancer

Cancer is a disease of evolution: cancer cells continually grow and change, and new mutations allow them to spread, even as treatments have continued to improve.

10 Jan 2020

Study demonstrates accuracy of AI system in diagnosing prostate cancer

The Lancet Oncology has today published the results of a study demonstrating the accuracy of an artificial intelligence system in diagnosing prostate cancer in tissue samples.

10 Jan 2020

Siah2 Gene Control could Help Treat Melanomas More Effectively

To develop improved cancer immunotherapies, it is essential to understand how cancers shut down the natural immune response to foreign antigens. This current study demonstrates how mice lacking the Siah2 gene, fail to develop BRAF-mutation carrying melanoma from the corresponding cells, completely rejecting them. This could help in boosting the anticancer effect of existing specific immune checkpoint inhibitors, such as anti-PD-1 drugs.

10 Jan 2020