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Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

Advancing neurotoxicity research with INTEGRA pipettes

INTEGRA Biosciences has awarded 31 EVOLVE manual pipettes, GRIPTIPS® pipette tips worth US $1000, and lab accessories to the bioanalytical company DNTOX as part of its recent ‘INTEGRA supports start-ups’ competition, which ran until April 2023.

From INTEGRA Biosciences 10 Oct 2023

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells).

9 Oct 2023

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Using antigenic cartography, researchers analyzed cross-reactivity patterns of SARS-CoV-2 variants and the effect of spike-protein changes on post-infection and vaccination immune responses. The study illuminated unique neutralization profiles and underscored the evolving defense mechanisms with repeated immunizations.

8 Oct 2023

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

Recent study assesses NVX-CoV2373 vaccine's effectiveness against Omicron variant. Findings show decreased efficacy over four months, but stable protection against symptomatic COVID-19.

8 Oct 2023

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Researchers investigate whether ribavirin and pleconaril could stimulate endogenous insulin production among individuals with incident type 1 diabetes.

8 Oct 2023

Is HPV infection a hidden risk factor for prostate cancer?

In a comprehensive meta-analysis published in Scientific Reports, researchers unveil a significant link between human papillomavirus (HPV) infection and increased risk of prostate cancer, highlighting the importance of considering normal prostate tissues over benign prostatic hyperplasia (BPH) as controls for more accurate conclusions.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Using portable laboratory devices for rapid and sensitive on-site detection of SARS-CoV-2

A new study has demonstrated rapid and sensitive on-site detection of SARS-CoV-2 RNA from environmental surfaces using a portable laboratory device.

5 Oct 2023

Can human chorionic gonadotropin supplements enhance penile growth?

Whether human chorionic gonadotropin could expedite tunica albuginea restructuring to aid penile development.

4 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

Using a new recipe for growing blood vessels from living lung tissue in the lab, a University of Virginia School of Engineering and Applied Science research team has developed an analytical tool that could lead to a cure for idiopathic pulmonary fibrosis, or IPF, a lung-destroying disease.

3 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Ginger shows promise as a natural defense against autoimmune diseases

Comprehensive study reveals that whole ginger extracts have a significant impact on inhibiting neutrophil hyperactivity, a key factor in autoimmune diseases like APS and lupus. Consuming ginger for just a week showed promising results in both animal models and human trials, positioning it as a natural and affordable treatment option for a range of autoimmune disorders.

2 Oct 2023

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.

28 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Assay News and Research

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Advancing neurotoxicity research with INTEGRA pipettes

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Is HPV infection a hidden risk factor for prostate cancer?

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Using portable laboratory devices for rapid and sensitive on-site detection of SARS-CoV-2

Can human chorionic gonadotropin supplements enhance penile growth?

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Could infants' robust immune responses reshape future vaccination strategies?

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Ginger shows promise as a natural defense against autoimmune diseases

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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