Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Unique 3D printed system for wide-scale production of stem cells

Researchers have developed a unique 3D printed system for harvesting stem cells from bioreactors, offering the potential for high quality, wide-scale production of stem cells in Australia at a lower cost.

16 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

Cellular "barcoding" in mice unravels the origins of blood

The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications for blood cancers, bone marrow transplant, and immunology. Fernando Camargo, PhD, of the Stem Cell Program at Boston Children's Hospital led the study, published in Nature on June 15.

15 Jun 2022

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

With prompt diagnosis and the right treatment, people with HIV can live long, healthy lives. In recent years, however, gains in survival among people with HIV have exposed a new concern – an increase in the incidence of early-onset cardiovascular disease associated with long-term HIV.

14 Jun 2022

RNA exosomes play a key role in B cell development, UTSW study suggests

New research from UT Southwestern suggests that RNA exosomes – the cellular machines that degrade old molecules of RNA – play a key role in the development of B cells, which are critical to the immune system's ability to protect against infection.

13 Jun 2022

Study offers a new and unique treatment for AIDS

A new study from Tel Aviv University offers a new and unique treatment for AIDS which may be developed into a vaccine or a one time treatment for patients with HIV.

13 Jun 2022

Study sheds new light on the role of transcription factors in bone marrow microenvironments

In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them.

9 Jun 2022

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure.

8 Jun 2022

Oral pill taken once a day improves outcomes of patients with myelofibrosis

Momelotinib, an oral pill taken once a day, significantly improved outcomes of patients treated for myelofibrosis (MF), a rare but fatal bone marrow cancer, researchers reported June 7.

7 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022

ASU study explores components of the immune system

Unless you are an identical twin, you probably aren't often mistaken for someone else. Likewise, our own sense of self as distinct from all other humans is deeply ingrained since early childhood.

2 Jun 2022

Scientists unlock the cellular secrets of aging process

New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.

1 Jun 2022

Study shows how stress has a major impact on the immune system's ability to fight infections

Acute stress can be detrimental to fighting off infection, especially COVID-19, and increases the chance of dying in mouse models.

30 May 2022

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

26 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

The Sheri and Les Biller Family Foundation's $10 million gift will support City of Hope’s supportive care program for cancer patients

City of Hope, one of the largest cancer research and treatment organizations in the United States and a national leader in providing cancer patients with best-in-class, integrated supportive care programs, has received a $10 million gift from The Sheri and Les Biller Family Foundation.

24 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.