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Sons of fathers who smoke have 51% lower sperm count

Studies have repeatedly linked maternal smoking during pregnancy with reduced sperm counts in male offspring. Now a research team at Lund University in Sweden has discovered that, independently of nicotine exposure from the mother, men whose fathers smoked at the time of pregnancy had half as many sperm as those with non-smoking fathers.

22 Nov 2018

New method to extend cell division and immortalization of avian-derived cells

The number of critically endangered animals has been increasing in recent years. According to data from the International Union for the Conservation of Nature, 1375 avian species are categorized as being endangered animals, and around 12% of the endangered species are avian.

16 Nov 2018

Study defines biomarker in response to treatment of castration-resistant prostate cancer

The most aggressive type of prostate cancer, castration-resistant prostate cancer, can be treated with two different therapies: taxanes or hormone treatment. Until this day there are no comparative studies between the two and the decision on which treatment to use is done empirically and based on the patient's preferences.

14 Nov 2018

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers have provided new insight on the mechanisms behind the development of clear cell Renal Cell Carcinoma (ccRCC), according to new findings published in eLife.

13 Nov 2018

New study provides deeper insight into chromosome segregation during mitosis

When a cell divides—a process known as mitosis—its chromosomes need to be separated and evenly distributed into the newly created daughter cells. Although this is known to be extremely complicated and to feature a range of cellular components, many of its details remain unclear, which has hampered efforts to develop treatments for when mitosis goes awry.

12 Nov 2018

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Changing Perspectives of the Triggers of Cell Division

Cell division is integral to understanding development, growth and disease states such as cancer. It has long been known that for replication, a complete new set of DNA and the formation of a septum, dividing the two cells, are necessary. New research changes perspectives of how these two processes influence the timing of cell division.

8 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

UA scientists aim to identify drug targets for rare pediatric cancer

Rhabdomyosarcoma is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes).

1 Nov 2018

Researchers identify active stem cells in “resting zone” of cartilage

Researchers have discovered active chondrocytes within cartilage. The finding could help scientists understand bone abnormalities.

31 Oct 2018

Scientists describe novel conjugates made from antibodies and protein inhibitor

Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects--especially when treating tumors. In the journal Angewandte Chemie, scientists have now described novel conjugates made from antibodies and a kinesin spindle protein inhibitor.

31 Oct 2018

UC Riverside evolutionary biologist reveals why tall people are more prone to cancer

For most cancers, risk increases dramatically with age. But what about the effect of having more cells in the body? Might taller people be more prone to cancer because they have more cells?

26 Oct 2018

Novel drug extends survival for women with HR-positive metastatic breast cancer

The drug palbociclib, used in combination with standard treatment, improved survival for women with hormone receptor-positive metastatic breast cancer, according to a large phase III clinical trial.

24 Oct 2018

Tall people more likely to get cancers, finds study

A new study suggests that tall people are more likely to get cancers because they have more number of cells that can undergo dangerous mutations.

24 Oct 2018

Researchers discover new structure in human cells

A new structure in human cells has been discovered by researchers at Karolinska Institutet in Sweden in collaboration with colleagues in the UK.

22 Oct 2018

Newly discovered toxin stands out from others in the battle for microbial domination

A newly discovered toxin that some bacteria deploy to fend off competing bacteria stands out from others in the battle for microbial domination. While many deadly substances have been identified among bacteria, this previously unknown toxin behaves in a familiar way.

19 Oct 2018

Molding bacteria into unnatural shapes reveals the robustness of cell division

Researchers at OIST have shown that microbes can be molded into an array of unusual, elaborate shapes that are not seen in nature.

18 Oct 2018

Loss of tumor protein p53 helps cancer cells grow in hostile environment

Researchers have discovered a novel consequence of loss of the tumor protein p53 that promotes cancer development, according to new findings in eLife.

17 Oct 2018

Researchers demonstrate epigenetic memory transmission via sperm

A new study suggests that if the epigenetics of sperm chromosomes are altered by the environment a father experiences, then this could affect offspring’s health.

17 Oct 2018

Researchers identify basic relationships of cell cycle and cellular senescence in the placenta

Working with researchers from Stanford University and St. Anna Children's Cancer Research, researchers from Jürgen Pollheimer's laboratory at the Medical University of Vienna's Department of Obstetrics and Gynecology have now, for the first time, identified basic relationships of the cell cycle and cellular senescence in the human placenta.

15 Oct 2018