DNA Sequencing News and Research

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New study pinpoints complex genetic origins for autoimmune diseases

Scores of autoimmune diseases afflicting one in 12 Americans — ranging from type 1 diabetes, to multiple sclerosis (MS), to rheumatoid arthritis, to asthma — mysteriously cause the immune system to harm tissues within our own bodies. Now, a new study pinpoints the complex genetic origins for many of these diseases, a discovery that may lead to better diagnosis and ultimately to improved treatments.

30 Oct 2014

Genetic differences contribute to risk for autism

Small differences in as many as a thousand genes contribute to risk for autism, according to a study led by Mount Sinai researchers and the Autism Sequencing Consortium, and published today in the journal Nature.

29 Oct 2014

Researchers use DNA sequencing to uncover genes that heighten autism risk

In the largest study of its kind to date, researchers have used DNA sequencing to uncover dozens of genes that heighten the risk for autism. Joseph Buxbaum, Ph.D., Icahn School of Medicine at Mount Sinai, New York City, Mark Daly, Ph.D., Broad Institute of Harvard and MIT, and their colleagues examined more than 14,000 DNA samples from affected children, parents and unrelated people.

29 Oct 2014

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large, comprehensive gene searches. With this discovery, the altered gene, called RNF43, now ranks as one of the most common mutations in the two cancer types.

27 Oct 2014

Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

The work of one of the Stand Up To Cancer (SU2C) inaugural Dream Teams, launched in 2009 to focus on epigenetic therapy in cancer treatment, will continue with the commitment of $7.5 million from Van Andel Research Institute (VARI).

20 Oct 2014

Research on zebrafish helps identify cause of unknown genetic disorder

Research in zebrafish has helped identify the cause of an unknown genetic disorder affecting a boy and two of his uncles, scientists report in an article published October 14 in the journal GENETICS.

16 Oct 2014

$Researchers reveal gene variants that delay fracture healing$

Researchers reveal gene variants that delay fracture healing

Slow-healing or non-healing bone fractures in otherwise healthy people may be caused by gene variants that are common in the population, according to Penn State College of Medicine researchers.

15 Oct 2014

Penn State scientists find that mitochondrial disease more prevalent in older moms

The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children -- could provide valuable insights for genetic counseling.

14 Oct 2014

Four UCLA researchers receive NIH Director's New Innovator Award

Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health Director's New Innovator Award that will forward revolutionary stem cell and neuro-science in medicine.

12 Oct 2014

Discovery could lead to treatments for alcohol-related liver diseases

Researchers at the University of Missouri School of Medicine have identified epigenetic protein changes caused by binge drinking, a discovery that could lead to treatments for alcohol-related liver diseases.

9 Oct 2014

Lund University researchers identify mechanisms that play vital role in development of type 2 diabetes

By studying identical twins, researchers from Lund University in Sweden have identified mechanisms that could be behind the development of type 2 diabetes. This may explain cases where one identical twin develops type 2 diabetes while the other remains healthy.

7 Oct 2014

Scientists identify genetic factors that influence height in individuals

An international collaboration of scientists has identified a fifth of the genetic factors that cause height to vary between individuals.

6 Oct 2014

Researchers reveal 'programmable' antibiotic technique to target drug-resistant microbes

The multitude of microbes scientists have found populating the human body have good, bad and mostly mysterious implications for our health. But when something goes wrong, we defend ourselves with the undiscriminating brute force of traditional antibiotics, which wipe out everything at once, regardless of the consequences.

6 Oct 2014

Virginia Tech professor wins Paul L. Busch Award for outstanding work in water quality research

Amy Pruden, professor of civil and environmental engineering at Virginia Tech, is the 2014 recipient of the Paul L. Busch Award, including a $100,000 research grant.

1 Oct 2014

DNA sequencing may lead to greater care for patients with ventilator-associated pneumonia

A patient survives life-threatening trauma, is intubated in the intensive care unit (ICU) to support his or her affected vital functions, starts to recover, and then develops pneumonia.

23 Sep 2014

Researchers develop protein therapy that may stop cancer growth

A team of Stanford researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the blood stream and start aggressive new growths elsewhere in the body.

22 Sep 2014

MSU researchers show how bacterial immune systems fight off viruses

When this week's print issue of the journal Science comes out, a collective cheer will go up from New Mexico, Montana and even the Netherlands, thanks to the type of collaborative effort that is more and more the norm in these connected times. Yes, the research was brilliant, and if we're lucky, it will produce innovations in biology, medicine, biotechnology and agriculture. It could save lives, and it happened because this scientist talked with that one, that one knew another one, and brilliant minds overcame geographic distance to advance human understanding.

16 Sep 2014

DNA Sequencing News and Research

New study pinpoints complex genetic origins for autoimmune diseases

Genetic differences contribute to risk for autism

Researchers use DNA sequencing to uncover genes that heighten autism risk

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

Research on zebrafish helps identify cause of unknown genetic disorder

Researchers reveal gene variants that delay fracture healing

Penn State scientists find that mitochondrial disease more prevalent in older moms

Four UCLA researchers receive NIH Director's New Innovator Award

Discovery could lead to treatments for alcohol-related liver diseases

Lund University researchers identify mechanisms that play vital role in development of type 2 diabetes

Scientists identify genetic factors that influence height in individuals

Researchers reveal 'programmable' antibiotic technique to target drug-resistant microbes

Virginia Tech professor wins Paul L. Busch Award for outstanding work in water quality research

DNA sequencing may lead to greater care for patients with ventilator-associated pneumonia

Researchers develop protein therapy that may stop cancer growth

MSU researchers show how bacterial immune systems fight off viruses

Research gives scientists new insight into evolution of gibbon genome

Scientists find epigenetic link between mother's diet and offspring's risk of future obesity

Researchers reveal how alteration of single nucleotide could initiate fragile X syndrome

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