Endoplasmic reticulum (ER) News and Research

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Cardiac CT more effective in evaluating ER patients with chest pain

Cardiac computed tomography angiography scans (CT scans that look at the heart) can provide a virtually instant verdict on whether chest pain is from blockage of the coronary arteries.

28 Mar 2012

Detailed CT scan can safely and quickly rule out possibility of heart attack

A highly detailed CT scan of the heart can safely and quickly rule out the possibility of a heart attack among many patients who come to hospital emergency rooms with chest pain, according to the results of a study that will be presented by researchers from the Perelman School of Medicine at the University of Pennsylvania today at the American College of Cardiology's 61st Annual Scientific Session and published concurrently in the New England Journal of Medicine.

27 Mar 2012

PCI may be an excellent option for STEMI patients 90 years and older

Selected patients 90 years and older who experience an acute heart attack, or ST-elevation myocardial infarction (STEMI), have reasonable outcomes with coronary stenting, and should be considered for reperfusion therapy, based on a scientific poster being presented at the 61st annual American College of Cardiology (ACC) scientific session.

26 Mar 2012

Study validates Mitofusin 2 as possible target for treatment of diabetes mellitus

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause tissues to become insensitive to insulin, thus producing an increase in blood glucose concentrations. These are the two most common conditions prior to development of diabetes type 2.

26 Mar 2012

Deficiency of Mitofusin 2 protein leads to insulin resistance, glucose intolerance

The study shows that the lack of Mitofusin 2 in mice produces insulin resistance and glucose intolerance, the main causes of diabetes.

23 Mar 2012

Study provides important clue in type 1 diabetes

In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, JDRF-funded scientists from the Indiana University School of Medicine have found that a specific type of cellular stress takes place in pancreatic beta cells before the onset of T1D, and that this stress response in the beta cell may in fact help ignite the autoimmune attack.

23 Mar 2012

Endo acquires oxymorphone hydrochloride patent from Johnson Matthey

Endo announced today that it has acquired U.S. patent 7,851,482 B2 for oxymorphone hydrochloride, the key API in all formulations of OPANA, from Johnson Matthey plc.

23 Mar 2012

Roundup: States face new revenue downturn; Calif. county has disparities in life expectancy

Revenues in most U.S. states increased in the fourth quarter of 2011, but their recent surge is tapering off, as they grew just 2.7 percent from the final quarter of 2010, according to a report released on Monday. "This is a noticeable slowdown from the 11.1 (percent) and 6.1 percent year-over-year growth reported in the second and third quarters of 2011, respectively," the Rockefeller Institute, a think tank that closely watches states' revenues, said in the report.

21 Mar 2012

Synthetic marijuana use among teenagers raises concerns

According to reports three U.S. teenagers ended up in the emergency department with altered mental states and seriously elevated heart rates after smoking synthetic marijuana.

20 Mar 2012

ACEP urges public to learn how to prevent poison during 50th anniversary of NPPW

The American College of Emergency Physicians urges the public to learn how to "prevent poison" during the 50th Anniversary of National Poison Prevention Week (NPPW), March 18-24, 2012.

17 Mar 2012

Study identifies primary care skills and competencies in opioid risk management

Primary care physicians are faced with treating a large proportion of chronic pain patients, but many do not often have specific training in the assessment and management of chronic pain, including the use of opioid medications for chronic pain management.

17 Mar 2012

Research roundup: Medicaid vs. private pay ER use; Doctors treat black, white patients differently; Caregiver stress

By looking at National Health Interview Survey data of more than 230,000 patients from 1999-2009, researchers were able to compare Medicaid with privately insured patients. More than 39 percent of those enrolled in Medicaid in the sample used the ER versus 17.7 percent of privately insured patients. Medicaid patients wer much more likely to have "specific barriers to timely primary care."

17 Mar 2012

Harrington HealthCare introduces Strengthening Our Future campaign

Harrington HealthCare System today formally launched a fundraising campaign to rebuild the Emergency Department at its Webster campus, Harrington HealthCare at Hubbard. The $8.8 million Strengthening Our Future campaign will enable Harrington HealthCare at Hubbard to continue to deliver the highest quality care to its patients.

17 Mar 2012

Ultragenyx completes UX001 Phase 1 study on hereditary inclusion body myopathy

Ultragenyx Pharmaceutical Inc., a biotechnology company focused on developing treatments for rare and ultra-rare genetic disorders, today announced that the Phase 1 study of UX001 for hereditary inclusion body myopathy (HIBM) has been completed.

9 Mar 2012

State news: Several Mass. hospitals tie part of doctor pay to size of practice; Mass. officials push to alleviate crowds at ERs

Getting in to see a primary-care doctor at Massachusetts General and Brigham and Women's hospitals has for years been notoriously hard, with many popular practices closed to new patients. But now, reflecting dramatic shifts in health care, the prestigious hospitals are paying doctors more if they agree to accept new patients. The Harvard-affiliated hospitals are tying about 10 percent of doctors' salaries this year to the size of their practice and the complexity of their patients' illnesses.

6 Mar 2012

Cell-based test to discover molecules to treat ER-positive breast cancer

Cancer Research UK and its commercial arm, Cancer Research Technology have developed a unique test to discover molecules that could lead to potential new treatments for oestrogen receptor (ER)-positive breast cancer.

5 Mar 2012

HNSF, AAO publish new guideline on sudden hearing loss

On March 1, 2012, the American Academy of Otolaryngology-Head and Neck Surgery Foundation published a new Clinical Practice Guideline on Sudden Hearing Loss (SHL). This guideline is published as a supplement to Otolaryngology-Head and Neck Surgery.

2 Mar 2012

ER docs Medicaid complaint: Some patients denied coverage if diagnosis doesn't merit their care

Some states are not considering the symptoms that brought the patients to the hospital, the doctors charge. In other Medicaid news, Texas is looking at several options for Medicaid reform, Pennsylvania looks at human service program cuts, Wisconsin Democrats seek to stop reductions there and Minnesota officials respond to criticism from Sen. Charles Grassley.

2 Mar 2012

Americans visiting the ER for dental problems ignoring preventive services: Report

Latest figures show that more Americans are turning to the emergency room for routine dental problems. This choice often costs 10 times more than preventive care and offers far fewer treatment options than a dentist's office. This comes from an analysis of government data and dental research.

29 Feb 2012

First Edition: February 29, 2012

Today's headlines include reports on yesterday's GOP presidential primary elections and how health policy played a role in some of the rhetoric.

29 Feb 2012

Endoplasmic reticulum (ER) News and Research

Cardiac CT more effective in evaluating ER patients with chest pain

Detailed CT scan can safely and quickly rule out possibility of heart attack

PCI may be an excellent option for STEMI patients 90 years and older

Study validates Mitofusin 2 as possible target for treatment of diabetes mellitus

Deficiency of Mitofusin 2 protein leads to insulin resistance, glucose intolerance

Study provides important clue in type 1 diabetes

Endo acquires oxymorphone hydrochloride patent from Johnson Matthey

Roundup: States face new revenue downturn; Calif. county has disparities in life expectancy

Synthetic marijuana use among teenagers raises concerns

ACEP urges public to learn how to prevent poison during 50th anniversary of NPPW

Study identifies primary care skills and competencies in opioid risk management

Research roundup: Medicaid vs. private pay ER use; Doctors treat black, white patients differently; Caregiver stress

Harrington HealthCare introduces Strengthening Our Future campaign

Ultragenyx completes UX001 Phase 1 study on hereditary inclusion body myopathy

State news: Several Mass. hospitals tie part of doctor pay to size of practice; Mass. officials push to alleviate crowds at ERs

Cell-based test to discover molecules to treat ER-positive breast cancer

HNSF, AAO publish new guideline on sudden hearing loss

ER docs Medicaid complaint: Some patients denied coverage if diagnosis doesn't merit their care

Americans visiting the ER for dental problems ignoring preventive services: Report

First Edition: February 29, 2012

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