Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

In a recent study posted to the bioRxiv* preprint server, researchers from Spain, the United Kingdom, and the United States used chemical tools to uncover the molecular details of glycan-mediated modulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) processing.

19 Sep 2022

First Hand Experience in the Field of Clinical and Applied Mass Spectrometry

This Interview focuses on describing the Clinical and Applied Mass Spectrometry Program available at LOYOLA UNIVERSITY CHICAGO

From Loyola University Chicago Health Sciences Campus 16 Sep 2022

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

A new study maps the escape mutations found in various strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could cause them to escape neutralization by antibodies or detection by rapid antigen tests that rely on antibody binding for a positive result.

16 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

In a new study, researchers investigated the interactions between sirtuin 5 (SIRT5) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein (Nsp14) protein.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Role of the transketolase-like 1 gene in the development of the modern human brain

In a new study, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans.

12 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

Exposure to blue light may accelerate aging

A new study provides insights into the novel mechanisms through which blue light exposure interferes with non-retinal cell metabolic pathways in flies.

5 Sep 2022

Temporo-spatial pharmacometabolomics method to evaluate microregional effect of OLZ on brain tissue

Announcing a new article publication from Acta Pharmaceutica Sinica B. The brain is the most advanced organ with various complex structural and functional microregions.

5 Sep 2022

Respiratory diseases affect females and males differently, study says

The impact of breathing diesel exhaust fumes may be more severe for females than males, according to new research that will be presented at the European Respiratory Society International Congress in Barcelona, Spain.

2 Sep 2022

New labeling technique helps analyze the contents of exosomes from cells

Our cells are constantly communicating, and scientists have developed an efficient way to find out what messages they are sending in protein-packed biological suitcases called exosomes.

30 Aug 2022

Exploration of glycan shield structure of sarbecoviruses provides new insights into developing pan-coronavirus vaccines

A new study explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for developing broad-range pan-coronavirus vaccines.

30 Aug 2022

Study identifies novel neutrophil biomarkers of delayed recovery in COVID-19

Researchers map the proteomes of peripheral blood neutrophils isolated from hospitalized COVID-19 patients using high-resolution LC-MS.

25 Aug 2022

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Researchers explored how the natural alterations inside the SARS-CoV-2 glycan barrier affect the spike protein dynamics.

22 Aug 2022

Intake of lysine prevents hypertensive kidney disease in animal models

Can you eat your way out of a kidney disease? Perhaps you can – according to a new study from Aarhus University.

19 Aug 2022

Researchers create novel mouse model for mapping protein communication between organs

Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources.

17 Aug 2022

Novel AI algorithm predicts the risk of mortality for patients suffering a major injury

Scientists from the Department of Traumatology and Acute Critical Medicine at the Osaka University Graduate School of Medicine developed an AI algorithm to predict the risk of mortality for patients suffering a major injury. Using the Japan Trauma Data Bank for the years 2013 to 2017, they were able to obtain records for over 70,000 patients who had experienced blunt-force trauma, which allowed the researchers to identify critical factors that could guide treatment strategies more precisely.

17 Aug 2022

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Researchers evidenced the presence of SARS-CoV-2 in the human brain, infecting astrocytes and impairing neuronal function and viability.

15 Aug 2022

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

Researchers explored how passive administration of monoclonal antibodies impact the development of immunological memory in response to COVID-19 vaccination.

15 Aug 2022

Mass Spectrometry News and Research

Further Reading

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

First Hand Experience in the Field of Clinical and Applied Mass Spectrometry

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Role of the transketolase-like 1 gene in the development of the modern human brain

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Exposure to blue light may accelerate aging

Temporo-spatial pharmacometabolomics method to evaluate microregional effect of OLZ on brain tissue

Respiratory diseases affect females and males differently, study says

New labeling technique helps analyze the contents of exosomes from cells

Exploration of glycan shield structure of sarbecoviruses provides new insights into developing pan-coronavirus vaccines

Study identifies novel neutrophil biomarkers of delayed recovery in COVID-19

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Intake of lysine prevents hypertensive kidney disease in animal models

Researchers create novel mouse model for mapping protein communication between organs

Novel AI algorithm predicts the risk of mortality for patients suffering a major injury

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

Enhancing confidence in chemical ionization spectrometry data eBook

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