Mitochondria News and Research

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SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Green tea shown to increase the defensive capabilities of cells

Green tea has been said to have a variety of health benefits. In this interview, we speak to Professor Micheal Ristow about his latest research into green tea.

3 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood.

30 Nov 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

Weekly exposure to deep red light in the morning can improve declining vision

Just three minutes of exposure to deep red light once a week, when delivered in the morning, can significantly improve declining eyesight, finds a pioneering new study by UCL researchers.

24 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Irregular body clock plays key role in driving inflammation in the immune cells, research shows

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

24 Nov 2021

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Since they hit the market, e-cigarettes have been touted as a safe alternative to tobacco cigarettes for adult smokers.

24 Nov 2021

Cancer cells disarm cellular attackers by extending out nanoscale tentacles

To grow and spread, cancer cells must evade the immune system. Investigators from Brigham and Women's Hospital and MIT used the power of nanotechnology to discover a new way that cancer can disarm its would-be cellular attackers by extending out nanoscale tentacles that can reach into an immune cell and pull out its powerpack.

18 Nov 2021

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, a team of researchers from the University of Pennsylvania's Perelman School of Medicine have found.

16 Nov 2021

Study analyzes the health effects of a patented DGA compound

A study conducted at the University of Jyväskylä analyzed the health effects of a patented DGA compound and compared them to the effects of exercise.

15 Nov 2021

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition.

12 Nov 2021

New computer program can read any genome sequence and decipher its genetic code

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

9 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.

29 Oct 2021

Mitochondrial proteins last much longer than expected, finds study

Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night. Scientists already know that our metabolic health can suffer when our biological clock breaks down, due to shift work or sleep disorders, for example. However, it's unclear how exactly the biological clock of people with type 2 diabetes differs from healthy people.

21 Oct 2021

Mitochondria News and Research

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Green tea shown to increase the defensive capabilities of cells

Novel anti-inflammatory drug target identified by CRISPR

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Weekly exposure to deep red light in the morning can improve declining vision

New technique may be a significant leap forward in the understanding of human cells

Irregular body clock plays key role in driving inflammation in the immune cells, research shows

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Cancer cells disarm cellular attackers by extending out nanoscale tentacles

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Study analyzes the health effects of a patented DGA compound

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

New computer program can read any genome sequence and decipher its genetic code

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Mitochondrial proteins last much longer than expected, finds study

A novel approach to improve the stability of Remdesivir

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

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