Mouse Model News and Research

RSS

Study hints at a promising approach for treating wet age-related macular degeneration

A new study in mice hints at the promise of an eventual alternative treatment option for the "wet" version of age-related macular degeneration (AMD).

2 Jul 2024

Researchers identify key osteoporosis-related gene and develop new mouse model of the disease

Osteoporosis - weakening of the bones with age - affects millions worldwide, and this figure is increasing annually as the global population ages.

1 Jul 2024

Researchers discover role of particular protein in the development of lupus

A research team of Professor Yoontae Lee and Jiho Park, a PhD candidate, from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) recently discovered that a particular protein promotes the development of systemic lupus erythematosus (SLE).

1 Jul 2024

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models.

28 Jun 2024

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

A study in "Nutrients" explores how rapeseed diacylglycerol oil (RDG) affects fat accumulation and metabolism in obese mice, showing significant benefits in reducing obesity-related indices and improving lipid metabolism.

26 Jun 2024

Study reveals novel therapeutic approach for excessive alcohol use

In a significant finding, researchers from The Jackson Laboratory (JAX) and UConn Health have discovered that sodium valerate, a short-chain fatty acid produced by gut microbes, can dramatically reduce binge drinking behavior and blood ethanol concentration in mice.

25 Jun 2024

Senecavirus A could be a promising new therapeutic approach for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a highly aggressive tumor with limited treatment options and high mortality.

25 Jun 2024

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

The link between severe headache disorders headaches and the body's circadian clock in pain timing and thresholds will be studied with a $2.4 million grant from the National Institute of Neurological Disorders and Stroke (NINDS) to UTHealth Houston researchers.

21 Jun 2024

Integrated cellular map of heart cells unlocks cardiac fibrosis process

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

21 Jun 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

13 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Macrophages play an unexpected role in the complicated obesity-cancer connection

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Pre-clinical trials: A new therapeutic approach for the severe condition uses modified viruses to replace a missing protein in the brain.

7 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Targeting synaptic lipid signaling: A novel approach to mental health treatment

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders.

6 Jun 2024

Mouse Model News and Research

Study hints at a promising approach for treating wet age-related macular degeneration

Researchers identify key osteoporosis-related gene and develop new mouse model of the disease

Researchers discover role of particular protein in the development of lupus

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

Study reveals novel therapeutic approach for excessive alcohol use

Senecavirus A could be a promising new therapeutic approach for hepatocellular carcinoma

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

Integrated cellular map of heart cells unlocks cardiac fibrosis process

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Macrophages play an unexpected role in the complicated obesity-cancer connection

Enhancing CAR-T cell therapy with biodegradable scaffolds

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Targeting synaptic lipid signaling: A novel approach to mental health treatment

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News